Evidence map›Paper›PMID 40760263›Full record

ReviewJournal of imaging informatics in medicine2026

Digital Twin Technology In Radiology.

Sara Sadat Aghamiri, Rada Amin, Pouria Isavand, Sanaz Vahdati, Atefeh Zeinoddini, Felipe C Kitamura, Linda Moy, Timothy Kline

Abstract readReview
In one paragraph

Review in Journal of imaging informatics in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sara Sadat AghamiriDecision Neuroscience Laboratory, Center for Brain, Biology, and Behavior, University of Nebraska, Lincoln, NE, 68503, USA. saghamiri2@unl.edu.ORCID http://orcid.org/0000-0003-4440-7059
Rada AminCancer Digital Twin, San Mateo, CA, USA.
Pouria IsavandMultiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Sanaz VahdatiMayo Clinic Artificial Intelligence Laboratory, Department of Radiology, Mayo Clinic, Rochester, MN, USA.
Atefeh ZeinoddiniDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Felipe C KitamuraDepartment of Diagnostic Imaging, Universidade Federal de São Paulo, Rua Napoleão de Barros 800, São Paulo, SP, 04024-000, Brazil.
Linda MoyDepartment of Radiology, New York University Grossman School of Medicine, New York, USA.
Timothy KlineDepartment of Radiology, Mayo Clinic, Rochester, MN, USA. Kline.Timothy@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A digital twin is a computational model that provides a virtual representation of a specific physical object, system, or process and predicts its behavior at future time points. These simulation models form computational profiles for new diagnosis and prevention models. The digital twin is a concept borrowed from engineering. However, the rapid evolution of this technology has extended its application across various industries. In recent years, digital twins in healthcare have gained significant traction due to their potential to revolutionize medicine and drug development. In the context of radiology, digital twin technology can be applied in various areas, including optimizing medical device design, improving system performance, facilitating personalized medicine, conducting virtual clinical trials, and educating radiology trainees. Also, radiologic image data is a critical source of patient-specific measures that play a role in generating advanced intelligent digital twins. Generating a practical digital twin faces several challenges, including data availability, computational techniques, validation frameworks, and uncertainty quantification, all of which require collaboration among engineers, healthcare providers, and stakeholders. This review focuses on recent trends in digital twin technology and its intersection with radiology by reviewing applications, technological advancements, and challenges that need to be addressed for successful implementation in the field.

Indexed as

RadiologyComputer SimulationHumansArtificial intelligenceDigital twinsImaging informaticsPersonalized medicineRadiology

Identifiers

PMID40760263
PMCPMC13103116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.