Evidence map›Paper›PMID 40760236›Full record

ArticleCardiovascular engineering and technology2025

Bare Metal Stenting for Residual Arch Dissections: A Computational Analysis.

Žiga Donik, Sanjeev Dhara, Willa Li, Blessing Nnate, Seth Sankary, Kayla Polcari, Mary Alyssa Varsanik, Kameel Khabaz, Ross Milner, Nhung Nguyen and 2 more

Abstract read
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In one paragraph

Article in Cardiovascular engineering and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Žiga Donik *Faculty of Mechanical Engineering, University of Maribor, Maribor, Slovenia.
Sanjeev Dhara *Section of Vascular Surgery and Endovascular Therapy, Department of Surgery, The University of Chicago, Chicago, IL, USA. Sanjeev.Dhara@bsd.uchicago.edu.ORCID 0000-0002-3906-5923
Willa LiSection of Vascular Surgery and Endovascular Therapy, Department of Surgery, The University of Chicago, Chicago, IL, USA.
Blessing NnateSection of Vascular Surgery and Endovascular Therapy, Department of Surgery, The University of Chicago, Chicago, IL, USA.
Seth SankarySection of Vascular Surgery and Endovascular Therapy, Department of Surgery, The University of Chicago, Chicago, IL, USA.
Kayla PolcariSection of Vascular Surgery and Endovascular Therapy, Department of Surgery, The University of Chicago, Chicago, IL, USA.
Mary Alyssa VarsanikSection of Vascular Surgery and Endovascular Therapy, Department of Surgery, The University of Chicago, Chicago, IL, USA.
Kameel KhabazSection of Vascular Surgery and Endovascular Therapy, Department of Surgery, The University of Chicago, Chicago, IL, USA.
Ross MilnerSection of Vascular Surgery and Endovascular Therapy, Department of Surgery, The University of Chicago, Chicago, IL, USA.
Nhung NguyenSection of Vascular Surgery and Endovascular Therapy, Department of Surgery, The University of Chicago, Chicago, IL, USA.
Janez KrambergerFaculty of Mechanical Engineering, University of Maribor, Maribor, Slovenia.
Luka PocivavsekSection of Vascular Surgery and Endovascular Therapy, Department of Surgery, The University of Chicago, Chicago, IL, USA. lpocivavsek@bsd.uchicago.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeType A Thoracic Aortic Dissections are a highly morbid and complex clinical challenge often managed with hemiarch or total arch repair. Hemiarch repair is more commonly performed due to improved neurologic morbidity profile however it leaves behind a residual dissection flap which can lead to aneurysmal degeneration. Bare metal stent placement in conjunction with hemiarch repair is a novel technique which can theoretically avoid leaving a residual dissection flap. In this paper we analyze the biomechanical changes observed after in silico deployment of a bare metal stent in a post-hemiarch type A aortic dissection.

methodsWe obtain computed tomography scans from pre-operative bare metal stent patients and perform high-fidelity segmentations. This geometry is then utilized for in silico stent deployment via finite element analysis. Deformed geometries are then utilized for computational fluid dynamic simulations to analyze the evolution of pressure gradients in the aorta.

resultsWe analyze the resulting geometry from in silico stent deployment for three different stiffness ratios between the flap and aortic wall. We demonstrate an acceptable stress evolution in the stent across all 3 stiffness configurations. We show a reduction in the false luminal volume across all stiffness ratios. Our analysis of pressure distributions that evolve in the aorta show that even in scenarios of high flap stiffness, where the false lumen volume shrinks correspondingly less, we still achieve a reduction in the pressure gradient across the aorta.

conclusionWe show that bare metal stent deployment hemodynamically stabilizes the aorta via our finite element analysis and subsequent computational fluid dynamic modelling.

Indexed as

Aorta, ThoracicAortic Aneurysm, ThoracicAortic DissectionBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationEndovascular ProceduresMetalsModels, CardiovascularPatient-Specific ModelingStentsAortographyComputed Tomography AngiographyComputer SimulationFinite Element AnalysisHemodynamicsHumansMetalsBare metal stentComputational fluid dynamicsFinite element analysisType A thoracic aortic dissection

Identifiers

PMID40760236
PMCPMC12686075

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.