Evidence map›Paper›PMID 40760125›Full record

ArticleSurgical and radiologic anatomy : SRA2025

Persistence of the midline septum of the odontoid process: anatomical and radiological study.

Joe Iwanaga, Rarinthorn Samrid, Norio Kitagawa, Basem Ishak, Hisaaki Uchikado, Sassan Keshavarzi, Christopher M Maulucci, Aaron S Dumont, R Shane Tubbs

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Article in Surgical and radiologic anatomy : SRA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Joe IwanagaDepartment of Neurosurgery, Tulane Neuroscience Research Center, Tulane University School of Medicine, 131 S. Robertson St., Suite 1300, New Orleans, LA, 70112, USA. iwanagajoeca@gmail.com.
Rarinthorn SamridDepartment of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Norio KitagawaDepartment of Oral and Maxillofacial Anatomy, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Basem IshakDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Hisaaki UchikadoUchikado Neuro-Spine Clinic, Fukuoka, Fukuoka, Japan.
Sassan KeshavarziDepartment of Neurosurgery, Tulane Neuroscience Research Center, Tulane University School of Medicine, 131 S. Robertson St., Suite 1300, New Orleans, LA, 70112, USA.
Christopher M MaulucciDepartment of Neurosurgery, Tulane Neuroscience Research Center, Tulane University School of Medicine, 131 S. Robertson St., Suite 1300, New Orleans, LA, 70112, USA.
Aaron S DumontDepartment of Neurosurgery, Tulane Neuroscience Research Center, Tulane University School of Medicine, 131 S. Robertson St., Suite 1300, New Orleans, LA, 70112, USA.
R Shane TubbsDepartment of Neurosurgery, Tulane Neuroscience Research Center, Tulane University School of Medicine, 131 S. Robertson St., Suite 1300, New Orleans, LA, 70112, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring our screening of the computed tomography (CT) images of the craniocervical junction, we noticed that the odontoid process occasionally contains a highly ossified region in the midline consistent with a bony septum. Given its potential significance, this study aimed to investigate the highly ossified region in the midline of the odontoid process and to discuss its clinical relevance.

methodsEleven C2 vertebrae from formalin-embalmed cadaveric heads were assigned to micro-CT examination. When the midline septum was confirmed, gross anatomical and histological observations were performed. Another 20 dry adult C2 vertebrae were randomly chosen, and the midline septum was investigated using gross anatomical and histological observations.

resultsOverall prevalence of the midline septum was 22.6% (7/31) (36.7% with cadaveric C2 using micro-CT and 15% in dry C2). The midline septa were found within the anterior two-thirds in the axial view and superior two-thirds in the coronal view. The midline septum in each sample varied in its shape.

conclusionsTo our knowledge, this is the first study of the persistence of the midline septum of the odontoid process. We found the overall prevalence of this septum was 22.6%. All of the midline septa were found within the anterior two-thirds in the axial view and superior two-thirds in the coronal view. Future clinical studies are necessary to further explore its potential biomechanical and surgical significance, particularly in influencing odontoid fracture patterns.

Indexed as

Odontoid ProcessAdultAgedAged, 80 and overAnatomic VariationCadaverFemaleHumansMaleMiddle AgedX-Ray MicrotomographyAnatomyAxisCadaverCervical vertebraComputed tomographyDensHistologyOdontoid fractureOdontoid processSpine surgery

Identifiers

PMID40760125
PMCPMC12321927

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.