Evidence map›Paper›PMID 40760118›Full record

ArticleEuropean radiology2026

Bake your phantom-low-cost recipes for dough-based, tissue-mimicking CT phantoms.

Sonja Wichelmann, Florian Weiler, Thomas Friedrich, Joerg Barkhausen, Roman Kloeckner, Franz Wegner, Malte Maria Sieren

Abstract read
In one paragraph

Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sonja WichelmannFraunhofer Institute for Digital Medicine MEVIS, Lübeck, Germany. sonja.wichelmann@mevis.fraunhofer.de.ORCID http://orcid.org/0000-0002-2908-299X
Florian WeilerFraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany.ORCID http://orcid.org/0000-0002-5647-4577
Thomas FriedrichFraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Lübeck, Germany.ORCID http://orcid.org/0000-0002-5907-4245
Joerg BarkhausenInstitute of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Lübeck, Germany.ORCID http://orcid.org/0000-0001-8937-1198
Roman KloecknerInstitute of Interventional Radiology, University Hospital Schleswig-Holstein, Lübeck, Germany.ORCID http://orcid.org/0000-0001-5492-4792
Franz Wegner *Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Lübeck, Germany.ORCID http://orcid.org/0000-0001-5969-3428
Malte Maria Sieren *Institute of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Lübeck, Germany.ORCID http://orcid.org/0000-0002-3669-2892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePhantoms are essential for minimizing radiation-intensive experiments on humans and enhancing patient safety through model-based teaching and experimentation. While many phantoms are commercially available, their widespread use is limited by manufacturing complexity and high costs. This study aims to demonstrate a dough-based method to create customizable, realistic CT phantoms using affordable, readily available ingredients. MATERIALS AND

methodsFor this study, various doughs composed of flour, salt, water, and oil were created, scanned, and evaluated to assess their suitability for CT applications. Additionally, the effects of storage conditions, preservation, and temperature variations were analyzed. As an example, a liver was segmented from a 3D CT scan, scaled to 1:2, and a negative mold was 3D printed. The mold was subsequently filled with the most suitable dough composition to replicate the organ's anatomy and density.

resultsThe evaluation of the scanned ingredients and doughs demonstrated that Hounsfield unit (HU) values ranging from below -200 HU to above 1200 HU can be achieved, enabling the simulation of various human tissue densities. Based on the analysis, simple recipes are proposed to replicate radiodensities of different anatomical structures. Additionally, the results from the liver phantom confirm the feasibility of mimicking liver tissue and morphology.

conclusionsCT phantoms with specific radiodensities, mimicking human tissues, can be created using simple dough recipes, as demonstrated with our liver CT phantom. Refrigeration or freezing extends usability for a longer time, but temperature effects must be considered to ensure accurate HU values in CT scans. KEY POINTS: Question CT phantoms are costly and complex, limiting accessibility for customized imaging studies. Can common ingredients from the kitchen be used to create tissue-mimicking phantoms? Findings The dough-based phantoms simulated radiodensities from -200 to 1200+ HU, enabling the simulation of various human tissue densities. Clinical relevance Affordable, anatomically accurate CT phantoms can be made from kitchen ingredients for training and research, as demonstrated with our liver CT phantom.

Indexed as

Phantoms, ImagingTomography, X-Ray ComputedFlourHumansLiverPrinting, Three-DimensionalLiverModels (anatomic)Phantoms (Imaging)Printing (3D)Tomography (X-ray computed)

Identifiers

PMID40760118
PMCPMC12953410

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.