Evidence map›Paper›PMID 40760057›Full record

ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2025

Prevalence and impact of preoperative osteoporosis on healthcare utilization and patient-reported outcomes in primary total knee arthroplasty.

Alvaro Ibaseta, Ahmed K Emara, Benjamin E Jevnikar, Shujaa T Khan, Ignacio Pasqualini, Oguz Turan, Cleveland Clinic Adult Reconstruction Research, Nicolas S Piuzzi

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Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Alvaro IbasetaCleveland Clinic, Cleveland, USA.
Ahmed K EmaraCleveland Clinic, Cleveland, USA.
Benjamin E JevnikarCleveland Clinic, Cleveland, USA.
Shujaa T KhanCleveland Clinic, Cleveland, USA.
Ignacio PasqualiniCleveland Clinic, Cleveland, USA.
Oguz TuranNortheast Ohio Medical University, Ravenna, USA.
Cleveland Clinic Adult Reconstruction ResearchCleveland Clinic, Cleveland, USA.
Nicolas S PiuzziCleveland Clinic, Cleveland, USA. piuzzin@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOsteoporosis is a well-recognized risk factor for complications after total knee arthroplasty (TKA). However, the effect of pre-TKA osteoporosis on healthcare utilization and patient-reported outcomes is poorly understood. Here, we characterize the association between pre-TKA osteoporosis and (1) healthcare utilization and patient-reported pain and function outcome measures; and (2) dual X-ray absorptiometry (DEXA) scan T-scores and the aforementioned outcomes.

methodsA prospective cohort of primary elective TKA patients between July 2015 and January 2020 was obtained (n = 6318), of which 4922 (77.9%) completed 1-year follow-up. Outcomes included healthcare utilization (prolonged length of stay (LOS) ≥ 3D, discharge disposition (DD), 90-day readmission, and 1-year reoperation) as well as Knee Injury and Osteoarthritis Outcome Score (KOOS) Pain, KOOS-function (PS) and satisfaction.

resultsThe prevalence of pre-TKA osteoporosis was 66.8%, of which 28.7% had a DEXA scan and 66.3% were on osteoporosis medications. Medicated osteoporotic patients were independently associated with higher odds of prolonged LOS (Odds Ratio (OR): 1.21 (95% Confidence Interval (CI) 1.02-1.43)) and non-home DD (OR:1.56 (95%CI 1.25-1.95)). Medicated and non-medicated osteoporosis patients were associated with higher odds of 90-day readmission. The odds of failing to achieve MCID or satisfaction were not associated with preoperative OP diagnosis.

conclusionTwo-thirds of primary TKA recipients had osteoporosis. Among these patients, two-thirds were on medication and one-third had a DEXA scan. Osteoporotic patients are at a higher risk of 90-day hospital readmission, longer hospital stays and non-home discharge. Interestingly, osteoporosis status was not associated with failure to achieve clinically significant improvements or satisfaction at 1 year following TKA.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneeOsteoporosisPatient Acceptance of Health CarePatient Reported Outcome MeasuresAbsorptiometry, PhotonAgedFemaleHumansLength of StayMaleMiddle AgedPatient ReadmissionPatient SatisfactionPostoperative ComplicationsPrevalenceDischarge dispositionHospital readmissionLength of stayOsteoporosisPrimary total knee arthroplastyPROMs

Identifiers

PMID40760057
PMCPMC12321912

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.