Evidence map›Paper›PMID 40759944›Full record

ArticleBMC ophthalmology2025

The efficacy of the three-port bimanual technique for direct perfluorocarbon liquid-silicone oil exchange in vitrectomy for the treatment of advanced proliferative vitreoretinopathy.

Zhou Zhang, Xi Zhang, Mei Wang, Peng Chen, Guoxin Ding, Xian Wang, Yingqi Li

Abstract readComparative Study
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Zhou Zhang *The Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Xi Zhang *The Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Mei WangAier Eye Hospital (Gui Yang), Changsha, China.
Peng ChenBright Eye Hospital (Gui Zhou), Chengdu, China.
Guoxin DingThe Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Xian WangThe Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Yingqi LiThe Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China. 15902604087@163.com.

Funding

National Natural Science Foundation of China 82260204
6 · The paper itself

Abstract

purposeTo evaluate the therapeutic effect of three-port, bimanual technique for direct perfluorocarbon liquid (PFCL)-silicone oil (SO) exchange in avoiding retinal re-detachment and shortening the surgical duration in 23-gauge (23 G) pars plana vitrectomy (PPV) for the treatment of advanced proliferative vitreoretinopathy (PVR) complicating primary rhegmatogenous retinal detachment (RRD).

methodsA Retrospective, comparative, consecutive, single-center study was conducted. Fifty-one eyes of 51 patients diagnosed with RRD complicated by PVR at the severe C stage, according to the standardized grading system, were retrospectively reviewed over a 3-year period. All patients underwent three-port 23 G PPV following a standardized protocol. Twenty-three eyes underwent the bimanual technique for direct PFCL-SO exchange during the final surgical steps, while twenty-eight eyes received conventional air-fluid exchange (AFE) for PFCL removal before SO tamponade. Primary outcome measures included visual acuity (logMAR), retinal status, intraocular pressure (IOP), surgical time and incidence of intraoperative and postoperative complications over a minimum 12-month follow-up period.

resultsThe primary anatomical success rate was 86.9% in the bimanual group versus 85.7% in the AFE group (P = 0.898). Visual acuity on postoperative day 1 was significantly improved in the bimanual group compared with the AFE group (P = 0.022). The surgical duration of bimanual group was significantly reduced compared to that of AFE group (P < 0.001). Two eyes in AFE group developed intraocular lens decentration during the surgical procedure. No statistically significant differences were observed in the incidence of postoperative complications between groups.

conclusionThe bimanual technique for direct PFCL-SO exchange is advantageous for enhancing the efficiency of surgical procedures, reducing the incidence of intraoperative complications and maintaining the re-flattened retina in the process of PFCL aspiration and SO injection. This novel approach presents a feasible and cost-effective strategy to enhance both operational efficiency and rapid visual rehabilitation in the immediate postoperative period.

Indexed as

EndotamponadeFluorocarbonsSilicone OilsVitrectomyVitreoretinopathy, ProliferativeAdultAgedFemaleFollow-Up StudiesHumansIntraocular PressureMaleMiddle AgedRetinal DetachmentRetrospective StudiesTreatment OutcomeFluorocarbonsSilicone OilsBimanual techniquePars plana vitrectomyPerfluorocarbon liquidProliferative vitreoretinopathyRetinal detachmentSilicone oil

Identifiers

PMID40759944
PMCPMC12323066

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.