ArticleBMC public health2025
Perioperative outcomes among older surgical patients with multimorbidity: a longitudinal study from Ethiopia.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Preoperative pathways in adults with multiple long-term conditions undergoing major surgery: a systematic review.BMJ open · 2026Pooled it
- Elective Lumbar Decompression With Fusion Is Associated With Increased Mortality Compared With Decompression Alone: A National Propensity-Matched Analysis of Aging Cohorts.Global spine journal · 2026Article
- Aging self-stereotypes and associated factors among elderly patients with multimorbidity undergoing elective surgery: a cross-sectional study.BMC geriatrics · 2026Article
- Determinants of 28-day perioperative mortality and postoperative length of hospital stay among geriatric patients: a two-center prospective follow-up study in Ethiopia.BMC geriatrics · 2026Article
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Abstract
backgroundMultimorbidity, particularly prevalent among older patients, represents a growing global health challenge. This study investigates the prevalence of multimorbidity and its relationship with perioperative outcomes among older patients undergoing major surgery in Ethiopia.
methodsThis longitudinal study was conducted at a tertiary teaching hospital in Northwest Ethiopia from June 01, 2019, to June 30, 2021. All consecutive older (aged 50+) patients who underwent major surgery during the study period were included. The primary outcome measure was estimating the prevalence of multimorbidity. Secondary outcome measures were the association between multimorbidity and 28-day perioperative mortality and length of hospital stay. A bivariable and multivariable modified Poisson regression was used to compute crude and adjusted relative risks, respectively, along with 95% confidence intervals (CIs) to assess the strength of association while adjusting for confounding covariates. A p-value < 0.05 was used to declare statistical significance.
resultsOf 874 patients who underwent major surgery, 234 (26.77%) patients had one comorbidity, and 94 (10.76%) patients had multimorbidity. Among all geriatric patients, 130 (14.87%) had hypertension, 34 (3.89%) had diabetes mellitus, and 29 (3.32%) had cancer. The most common multimorbidity combination was hypertension and diabetes (18 cases). The rates of perioperative mortality were higher in patients with multimorbidity compared with those with either one or no comorbidity (36.46% vs. 33.33% vs. 28.21%; p < 0.001). The risk of perioperative mortality after surgery among patients with multimorbidity was more than eight (adjusted relative risk = 8.07, 95% CI:2.39, 27.23) times higher than that of those with no comorbidity.
conclusionMultimorbidity in older surgical patients was common, and one in ten older patients undergoing major surgery had multimorbidity. Multimorbidity increases the risk of mortality among older patients following major surgery. We recommend targeted management of older surgical patients with multimorbidity by preoperative screening and optimization before surgery.
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