ArticleBMC neurology2025
Ruptured intracranial aneurysm with spontaneous occlusion of internal carotid artery: clinical characteristics, prognostic risk factors, and survival analysis.
Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
backgroundRuptured intracranial aneurysm (RIA) combined with internal carotid artery occlusion (ICAO) is a rare and serious vascular condition. We aimed to describe the clinical characteristics and outcomes of these patients.
methodsWe retrospectively analyzed cases of RIA with concurrent spontaneous ICAO from the Chinese Multicenter Aneurysm Database (CMAD). Logistic regression analysis was used to identify independent risk factors associated with patient prognosis. Cox proportional hazards model was performed to determine predictors of cumulative mortality.
resultsWe analyzed 52 cases of RIA with ICAO, including 41 unilateral and 11 bilateral cases. Among unilateral ICAO cases, aneurysms were ipsilateral in 8, contralateral in 16, and midline in 17. Treatment included coiling (31 cases), clipping (6 cases), and conservative management (15 cases). Prognosis was favorable in 26 cases and unfavorable in 17, including 12 deaths. Logistic regression identified Hunt-Hess grade IV-V, conservative treatment, and symptomatic cerebral infarction as independent risk factors for unfavorable outcome. Cox proportional hazards model found Hunt-Hess grade IV-V to be a predictor of mortality during the 2-year follow-up.
conclusionHunt-Hess grade, treatment, and in-hospital cerebral infarction independently predict unfavorable outcome, with grades IV-V linked to early death. ICAO may increase the risk of aneurysm rupture, highlighting the importance of aneurysm location and its related hemodynamic mechanisms in clinical management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.