Electroreductive amination of carboxylic acids by cobalt catalysis.

Huihua Bi, Zhizheng Chen, Changsheng Bi, Shuanglin Qu, Jie Liu

Abstract read

In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huihua BiCollege of Chemistry and Chemical Engineering, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China.

Zhizheng ChenCollege of Chemistry and Chemical Engineering, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China.

Changsheng BiCollege of Chemistry and Chemical Engineering, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China.

Shuanglin QuCollege of Chemistry and Chemical Engineering, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China. squ@hnu.edu.cn.ORCID http://orcid.org/0000-0002-8122-9848

Jie LiuCollege of Chemistry and Chemical Engineering, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China. jieliu@hnu.edu.cn.ORCID http://orcid.org/0000-0002-3105-4840

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22301073

6 · The paper itself

Abstract

Catalytic reduction of carboxylic acids to valuable chemicals is highly desirable yet challenging for both biomass conversion and organic synthesis. Here we describe an efficient and sustainable electrocatalytic hydrogenation of carboxylic acids with amines utilizing protons as the hydrogen source. The application of an earth-abundant cobalt complex enables electrochemical generation of a cobalt-hydride intermediate, which serves as the key catalytically active species for this reductive process. Obviating the need for flammable H

Identifiers

PMID40759900

DOI10.1038/s41467-025-62396-4

PMCPMC12322302

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.