ArticleInternational journal of implant dentistry2025
The next frontier in osseointegration: energy and speed as critical determinants and their enhancement by UV photofunctionalization.
Article in International journal of implant dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The surface-agnostic advantage for peri-implant health: UV photofunctionalization as a positive-sum strategy for biofilm suppression and soft-tissue barrier-a systematic review with qualitative synthesis.International journal of implant dentistry · 2026Pooled it
- Surface activation of Ti6Al4V via vacuum versus conventional ultraviolet photofunctionalization: physicochemical and biological insights.BMC oral health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to redefine biomechanical understanding of osseointegration by dissecting its multi-faceted nature—strength, stiffness, energy, and the speed of development—through in vivo analysis
methodsTitanium implants were placed bilaterally in rat femurs, with one side receiving ultraviolet (UV) photofunctionalization and the contralateral side serving as untreated control. Biomechanical push-in tests were performed at day 4, and weeks 1 to 3 post-implantation. Yield strength, elastic modulus, toughness, and energy were measured over time, and their rates of change were calculated to assess dynamic progression. Mineralization at the bone–implant interface was quantified using energy-dispersive X-ray spectroscopy.
resultsYield strength followed a second-degree growth curve, plateauing over time in control implants. Derivative analysis revealed that the speed of strength gain peaked early and then declined. In contrast, osseointegration energy steadily increased throughout healing, with its rate of gain accelerating over time. Yield strength correlated quadratically with peri-implant mineralized tissue, indicating early saturation, while energy and toughness showed a continuous linear relationship. UV photofunctionalization enhanced all biomechanical parameters. Notably, it accelerated early strength acquisition (up to 3-fold) and markedly increased both energy (up to 3.4-fold) and its rate of development (up to 4.9-fold).
conclusionsBy introducing energy and its speed as novel indices, this study offers a more dynamic and functionally relevant framework for evaluating osseointegration. UV photofunctionalization not only accelerates early mechanical stability but amplifies energy acquisition at the bone–implant interface, promoting faster and more robust development of mechanical resilience.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.