Evidence map›Paper›PMID 40759803›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Oral health assessment of end-of-life patients with cancer: Evaluating the diagnostic accuracy of the oral assessment guide and oral health assessment tool in prognosis prediction.

Mifumi Nakao, Maiko Shimosato, Naoki Sakane, Takeshi Nakashima

Abstract readComparative Study
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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Mifumi NakaoDepartment of Oral and Maxillofacial Surgery, National Hospital Organization Kumamoto Medical Center, 1-5, Ninomaru, Tyuuouku, Kumamoto City, Kumamoto Prefecture, Japan. eveyun.3.michan@gmail.com.ORCID http://orcid.org/0000-0003-3714-7308
Maiko ShimosatoDepartment of Oral and Maxillofacial Surgery, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.ORCID http://orcid.org/0000-0003-1734-9447
Naoki SakaneDivision of Preventive Medicine, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.ORCID http://orcid.org/0000-0002-2625-571X
Takeshi NakashimaDepartment of Oral and Maxillofacial Surgery, National Hospital Organization Kumamoto Medical Center, 1-5, Ninomaru, Tyuuouku, Kumamoto City, Kumamoto Prefecture, Japan.ORCID http://orcid.org/0000-0002-5593-7648

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe compared the Oral Assessment Guide (OAG) and Oral Health Assessment Tool (OHAT) to determine which tool more accurately predicts prognosis in end-of-life patients with cancer.

methodsThis retrospective study included 116 end-of-life patients with cancer. Oral conditions were assessed using the OAG and OHAT. We performed receiver operating characteristic curve analysis with survival prognosis as the endpoint and compared the area under the curve (AUC). Hazard ratios (HRs) and 95% confidence intervals were calculated for the scores in unhealthy conditions using the health status score for each tool as a reference.

resultsThe OAG had a significantly higher AUC at 14 days (0.78 vs. 0.71, p = 0.02) and 21 days (0.72 vs. 0.67, p = 0.03). After adjusting for age and performance status, lips showed significant differences on day 21 under mild/moderate condition (HR = 7.76) and on days 14 and 21 in the severe condition (HR = 38.57 and 38.57, respectively). Saliva showed significant differences on days 21 and 28 in the severe condition (HR = 5.70 and 3.80, respectively). Among the OAG-specific items, voice under severe condition on day 21 showed a significant difference (HR = 3.93), while no OHAT-specific items showed significant differences.

conclusionThe OAG had significantly higher prognostic accuracy at 14 and 21 days. The OAG-specific item voice may account for differences in diagnostic accuracy. The appropriate selection of an oral assessment tool enables the provision of patient-centered oral care, which is expected to alleviate discomfort and facilitate communication between patients and their families.

Indexed as

NeoplasmsOral HealthTerminal CareAdultAgedAged, 80 and overArea Under CurveFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesROC CurveSalivaArea under the curveEnd-of-life stagesOral assessment guideOral health assessment toolPatients with cancer

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.