Evidence map›Paper›PMID 40759774›Full record

ArticlePediatric surgery international2025

Surgical and nutritional outcomes of extremely low birth weight infants with enterostomy: a single-center retrospective study in China.

Huijia Lin, Jiajing Ge, Guoqiang Qi, Jinfa Tou, Xiaolu Ma, Zheng Chen

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Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Huijia LinDepartment of NICU, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Binsheng Road 3333, Binjiang District, Hangzhou, China.
Jiajing GeDepartment of NICU, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Binsheng Road 3333, Binjiang District, Hangzhou, China.
Guoqiang QiDepartment of Data and Information, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jinfa TouDepartment of Neonatal Surgery, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiaolu MaDepartment of NICU, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Binsheng Road 3333, Binjiang District, Hangzhou, China.
Zheng ChenDepartment of NICU, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Binsheng Road 3333, Binjiang District, Hangzhou, China. chenz@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated the outcomes of extremely low birth weight (ELBW) infants who underwent intestinal enterostomy.

methodsThis retrospective study included ELBW infants who were hospitalized from January 1, 2019, to December 31, 2023, and underwent enterostomy. Data regarding demographic information, complications, and outcomes were collected.

resultsIn total, 52 ELBW infants who underwent enterostomy were enrolled. Among them, 30 (57.7%) had necrotizing enterocolitis (NEC) and 10 (19.2%) had spontaneous intestinal perforation. Forty-seven infants survived at discharge. Twenty-nine infants developed intestinal failure, while 36 developed short bowel syndrome. The median gestational age in the intestinal failure group was 26.9 (1.9) weeks, lower than that of 27.2 (1.5) weeks in the non-intestinal failure group (p = 0.024). Infants with intestinal failure achieved full enteral nutrition at an average age of 112(32) days; this was significantly greater than the age of 71(41) days in the non-intestinal failure group (p < 0.001).

conclusionNEC was the main disease in ELBW infants undergoing intestinal enterostomy, with a high incidence of SBS and IF postoperatively. Infants with IF have a lower gestational age and a longer parenteral nutrition duration. This finding highlights the need for more rational nutritional strategies.

Indexed as

Enteral NutritionEnterocolitis, NecrotizingEnterostomyInfant, Extremely Low Birth WeightInfant, Premature, DiseasesIntestinal FailureChinaFemaleGestational AgeHumansInfant, NewbornIntestinal PerforationMalePostoperative ComplicationsRetrospective StudiesShort Bowel SyndromeEnterostomyExtremely low birth weightIntestinal failurePrognosis

Identifiers

PMID40759774

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