Evidence map›Paper›PMID 40759765›Full record

SynthesisPediatric surgery international2025

The impact of gender on pediatric surgical access and outcomes in Africa.

Sacha Williams, Olivia Serhan, Jenny Wang, Christian Guindi, Elena Guadagno, Maeve Trudeau, Emmanuel Ameh, Kokila Lakhoo, Dan Poenaru

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sacha WilliamsFaculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada. sachawilliams@gmail.com.ORCID http://orcid.org/0000-0002-5221-1913
Olivia SerhanFaculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Jenny WangFaculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Christian GuindiFaculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Elena GuadagnoHarvey E. Beardmore Division of Pediatric Surgery, Montreal Children's Hospital, McGill University Health Center, 1001 Decarie Boulevard, Montreal, QC, H4A 3J1, Canada.
Maeve TrudeauFaculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Emmanuel AmehDepartment of Paediatric Surgery, National Hospital, Abuja, Nigeria.
Kokila LakhooNuffield Department of Surgical Sciences, Paediatric Surgery, University of Oxford, Oxford, United Kingdom.
Dan PoenaruFaculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGirls, whose care is often affected by barriers steeped in gender inequity, may be at higher risk of poor surgical outcomes. This study explored the impact of gender on pediatric surgical care in Africa.

methodsDifferences in access to care and clinical outcomes for boys and girls were examined for pediatric surgical conditions that do not differ by physiological sex. A systematic review of African pediatric surgical studies ensued, followed by a random effects meta-analysis, and risk of bias assessment.

resultsOf the 12,281 records retrieved, 54 were selected for review. Most studies were retrospective (57.4%), single-site (94.4%), from Egypt, Nigeria, Ghana, or Ethiopia (55.6%), focused on gastrointestinal conditions (63.0%), published in 2010 or sooner (85.1%), had study durations of 5 years or less (68.5%), and cohorts of less than 200 children (57.4%). Sixty percent reported the outcome of mortality. Meta-analysis odds ratios revealed surgery was performed 3.6 times more often on boys (95% CI 2.6, 4.9); and mortality was 1.6 times greater for girls (95% CI 1.3, 2.0).

conclusionAfrican girls appear to face gender inequities in pediatric surgical care. Findings will be further explored in a mixed-methods study. LEVEL OF EVIDENCE: I.

Indexed as

Healthcare DisparitiesHealth Services AccessibilityPediatricsSurgical Procedures, OperativeAfricaChildFemaleHumansMaleSex FactorsGender disparitiesLMICsMortalitySurgical outcomes

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.