Evidence map›Paper›PMID 40759722›Full record

ArticleCommunications biology2025

Transcriptome-wide regulation of folate on neural mRNA m

Anrui Liu, Zhengyi Huo, Zihe Xu, Sisi Liu, Yuting Jiao, Rui Li, Yi Lu, Meng Yang, Jia Huang, Chen Huang and 1 more

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. RNA mActa pharmacologica Sinica · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anrui Liu *Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Zhengyi Huo *School of Life Sciences, South China Normal University, Guangzhou, China.
Zihe XuSchool of Life Sciences, South China Normal University, Guangzhou, China.
Sisi LiuGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Yuting JiaoSchool of Life Sciences, South China Normal University, Guangzhou, China.
Rui LiSchool of Life Sciences, South China Normal University, Guangzhou, China.
Yi LuSchool of Life Sciences, South China Normal University, Guangzhou, China.
Meng YangSchool of Life Sciences, South China Normal University, Guangzhou, China.
Jia HuangSchool of Life Sciences, South China Normal University, Guangzhou, China.
Chen HuangDr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China.
Xiaoyun WangGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. wang_xiaoyun@gibh.ac.cn.ORCID http://orcid.org/0000-0002-3000-6441

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32070615
6 · The paper itself

Abstract

Increasing evidence shows that folate can regulate neural gene function through DNA modification, while regulatory roles of folate in neural RNA modification remain largely unknown. Here we show that folate treatment significantly increased Drosophila mRNA m

Indexed as

AdenosineCarbonDrosophila melanogasterFolic AcidNeuronsRNA, MessengerTranscriptomeAnimalsBrainDrosophila ProteinsGene Expression RegulationHumansMethylationMiceAdenosineCarbonDrosophila ProteinsFolic AcidRNA, Messenger

Identifiers

PMID40759722
PMCPMC12321983

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.