Evidence map›Paper›PMID 40759605›Full record

ArticleInternational journal of stem cells2026

Induced Pluripotent Stem Cells derived CD71

Changyeong Kim, Kyung Hwan Park, Soo-Been Jeon, A-Reum Han, Ji Yoon Lee, Young-Sup Yoon

Abstract read
In one paragraph

Article in International journal of stem cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Changyeong KimSeverance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0003-9211-5189
Kyung Hwan ParkSeverance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0009-1581-7623
Soo-Been JeonResearch and Development Center, KarisBio Inc., Seoul, Korea.ORCID https://orcid.org/0009-0008-6475-6081
A-Reum HanResearch and Development Center, KarisBio Inc., Seoul, Korea.ORCID https://orcid.org/0000-0001-5225-2363
Ji Yoon LeeResearch and Development Center, KarisBio Inc., Seoul, Korea.ORCID https://orcid.org/0000-0002-7117-2681
Young-Sup YoonSeverance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0051-0935

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Induced pluripotent stem cells (iPSCs) are a promising cell source for regenerative medicine. Clinical applications require a large number of functional red blood cells (RBCs), making it essential to ensure the proliferation of actively dividing, nucleated erythroblasts derived from iPSCs. Small molecules can enhance the efficiency and frequency of iPSC-derived cell differentiation. Sirtuin 1, a key enzyme in multiple biological processes, has been implicated in enhancing iPSC-derived cell differentiation. However, the specific effects of Sirtuin 1 on erythroblast proliferation from iPSCs remain unclear. Here, we developed a protocol to examine the effects of Sirtuin 1 on erythroblasts after endothelial-to-hematopoietic transition (EHT). We found that Sirtuin 1 activation increased the frequency of CD71

Indexed as

CD71ErythroblastsErythropoiesisGlycophorinsInduced pluripotent stem cellSirtuin 1

Identifiers

PMID40759605
PMCPMC12954770

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.