Evidence map›Paper›PMID 40759591›Full record

ArticleThe world journal of men's health2026

Efficacy and Tolerability Outcomes of Minimally Invasive Surgical Treatments for Benign Prostatic Hyperplasia: A Random-Effects Network Meta-Analysis.

Brian Ng Hung Shin, Rebekah Maksoud, Samuel Tan, Handoo Rhee, Hyun Jun Park, Eric Chung

Abstract read
In one paragraph

Article in The world journal of men's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brian Ng Hung ShinDepartment of Urology, Princess Alexandra Hospital, The University of Queensland, Brisbane, Australia.ORCID https://orcid.org/0000-0003-4501-699X
Rebekah MaksoudDepartment of Urology, Princess Alexandra Hospital, The University of Queensland, Brisbane, Australia.
Samuel TanDepartment of Urology, Princess Alexandra Hospital, The University of Queensland, Brisbane, Australia.
Handoo RheeDepartment of Urology, Princess Alexandra Hospital, The University of Queensland, Brisbane, Australia.ORCID https://orcid.org/0000-0002-1722-7127
Hyun Jun ParkDepartment of Urology, Pusan National University Hospital, Busan, Korea.ORCID https://orcid.org/0000-0003-0566-9574
Eric ChungDepartment of Urology, Princess Alexandra Hospital, The University of Queensland, Brisbane, Australia.ORCID https://orcid.org/0000-0003-3373-3668

Funding

NeoTract, Inc.Pusan National University
6 · The paper itself

Abstract

purposeMinimally invasive surgical treatments (MIST) provide emerging alternatives to transurethral resection of the prostate (TURP) for benign prostatic hyperplasia (BPH). This network meta-analysis provides a comparative analysis of clinical efficacy and tolerability for individual MIST versus TURP in BPH. MATERIALS AND

methodsA PRISMA-compliant systematic review was performed by searching the PubMed, EMBASE, and Cochrane Library databases from inception to 31 August 2023. Eligible studies compared post-treatment change scores or relative risks between ≥2 distinct BPH interventions for International Prostate Symptom Score (IPSS), peak urinary flow rate (Qmax), post-void residual urine, Sexual Health Inventory in Men (SHIM) and Men's Sexual Health Questionnaire (MSHQ) scores, and re-intervention rate. Pairwise comparisons were synthesized through a random-effects frequentist model to determine aggregate estimates for treatment-outcome associations.

resultsOf 4,416 screened articles, 59 studies were included for quantitative analysis, comprising 21,078 patients across 47 unique cohorts. Prostatic arterial embolization (PAE) and Aquablation appeared to induce similar reductions in IPSS to TURP; however, there was insufficient data to evaluate the tolerability of PAE or Aquablation. Water vapor thermal therapy (WVTT) and prostatic urethral lift (PUL) were less efficacious at reducing IPSS than TURP but exhibited greater preservation of SHIM and MSHQ scores. TURP demonstrated the lowest relative risk of re-intervention.

conclusionsPAE and Aquablation appear to be efficacious approaches to BPH management, with PAE also producing a comparable increase in Qmax to TURP. WVTT and PUL appear less effective than TURP but are associated with lower risk of male sexual dysfunction.

Indexed as

Benign prostatic hyperplasiaClinical outcomesMinimal invasive surgerySexual functionSystematic review

Identifiers

PMID40759591
PMCPMC12798321

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.