Evidence map›Paper›PMID 40758578›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2025

Altered acute metabolic response to muscle stimulation in muscular dystrophic mice observed by phosphorus-31 magnetic resonance spectroscopy and fingerprinting.

Kihwan Kim, Yudu Li, Lauren G Koch, Zhi-Pei Liang, Xin Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kihwan KimDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States.
Yudu LiDepartment of Electrical and Computer Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States.
Lauren G KochDepartment of Physiology and Pharmacology, University of Toledo College of Medicine, Toledo, Ohio, United States.ORCID 0000-0002-2019-5939
Zhi-Pei LiangDepartment of Electrical and Computer Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States.
Xin YuDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States.ORCID 0000-0001-8996-0267

Funding

AQP4 and glymphatic function in post-stroke recoveryR01NS124206 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI Christopher A Flask, Xin Yu · 2022 to 2026
$2.8M
Phosphorus-31 MR Spectroscopic Imaging and FingerprintingR01EB023704 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI LIANG, ZHI-PEI, YU, XIN · 2017 to 2020
$1.8M
HHS | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) R01-EB23704HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01-NS124206NIBIB NIH HHS R01 EB023704NINDS NIH HHS R01 NS124206
6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration. Impaired muscle metabolism has been implicated in DMD, and interventions aimed at normalizing and enhancing metabolic function, such as exercise, have been proposed as potential therapeutic strategies. However, the metabolic response to exercise in DMD remains incompletely understood. This study aimed to investigate the acute metabolic response to muscle stimulation mimicking high-intensity exercise. Using phosphorus-31 magnetic resonance spectroscopy (

Indexed as

Muscle, SkeletalMuscular Dystrophy, DuchenneAnimalsCreatine KinaseDisease Models, AnimalMagnetic Resonance SpectroscopyMaleMiceMice, Inbred C57BLMice, Inbred mdxPhosphocreatinePhosphorus IsotopesPhysical Conditioning, AnimalCreatine KinasePhosphocreatinePhosphorus Isotopescreatine kinaseDuchenne muscular dystrophyexercisemetabolic functionphosphorus-31 magnetic resonance spectroscopy

Identifiers

PMID40758578
PMCPMC12369892

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.