Evidence map›Paper›PMID 40758505›Full record

ArticleIEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society2025

Unified Control of a Powered Knee-Ankle Prosthesis Enables Walking, Stairs, Transitions, and Other Daily Ambulation Activities.

Liam M Sullivan, Marissa Cowan, Lukas Gabert, Tommaso Lenzi

Abstract readValidation Study
In one paragraph

Article in IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Design and evaluation of a bone-anchored, neurally-controlled knee prosthesis.Journal of neuroengineering and rehabilitation · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liam M Sullivan
Marissa Cowan
Lukas Gabert
Tommaso Lenzi

Funding

Lightweight Powered Prosthesis for Above-knee AmputeesR01HD098154 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Tommaso Lenzi · 2019 to 2026
$3.6M
NICHD NIH HHS R01 HD098154
6 · The paper itself

Abstract

Conventional passive prostheses for lower limb amputees lack active assistance and cannot replicate the natural energy dynamics of healthy limbs, resulting in compromised mobility and diminished quality of life. Powered lower-limb prostheses can theoretically replicate the biomechanical function of healthy limbs during ambulation. However, existing powered prostheses fall short of fully restoring mobility for individuals with above-knee amputations. This limitation is mainly due to existing controllers, which struggle to coordinate their assistance with the user's movements across a variety of activities in a natural manner. This paper proposes a novel unified controller for powered knee and ankle prostheses that enables multiple activities and adapts to users and the environment. The proposed controller enables natural ambulation without requiring explicit measurements of the environmental characteristics or classification of the intended ambulation task. In experiments with three amputee subjects, the proposed controller enabled walking on level, inclined, and uneven ground, ascending/descending stairs, sitting and standing, and seamless transitions between these activities. This work presents the first implementation of a unified, task-agnostic control strategy for continuous ambulation across everyday ambulation activities for powered knee and ankle prostheses.

Indexed as

AmputeesArtificial LimbsRoboticsWalkingActivities of Daily LivingAdultAnkle JointBiomechanical PhenomenaFemaleHumansKnee JointLegMaleMiddle AgedProsthesis DesignQuality of Life

Identifiers

PMID40758505
PMCPMC12447845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.