Evidence map›Paper›PMID 40758465›Full record

ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2025

Subxiphoid Thoracoscopic Surgery Is Safe and Feasible for the Treatment of Anterior Mediastinal Teratomas: A Multicentre Retrospective Study.

Yunze Liu, Enwu Xu, Fanyi Kong, Guangjie Hou, Shiyun He, Chaoyang Liang, Yang Liu, Chengrun Li, Leilei Shen, Yanbin Pei and 2 more

Abstract readMulticenter Study
In one paragraph

Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yunze LiuThe Chinese PLA Medical School, Beijing 100853, China.
Enwu XuDepartment of Thoracic Surgery, General Hospital of Southern Theater Command, PLA, Guangzhou 510010, China.
Fanyi KongDepartment of Thoracic Surgery, Cangzhou Center Hospital, Cangzhou, Hebei 061012, China.
Guangjie HouDepartment of Thoracic Surgery, Henan Provincial People's Hospital, Zhengzhou, Henan 462000, China.
Shiyun HeDepartment of Thoracic Surgery, General Hospital of Southern Theater Command, PLA, Guangzhou 510010, China.
Chaoyang LiangThe First Medical Center, Department of Thoracic Surgery, Chinese General Hospital of PLA, Beijing 100853, China.
Yang LiuThe First Medical Center, Department of Thoracic Surgery, Chinese General Hospital of PLA, Beijing 100853, China.
Chengrun LiThe First Medical Center, Department of Thoracic Surgery, Chinese General Hospital of PLA, Beijing 100853, China.
Leilei ShenDepartment of Thoracic Surgery, The Hainan Hospital of Chinese General Hospital of PLA, Sanya 572013, China.
Yanbin PeiThe First Medical Center, Department of Thoracic Surgery, Chinese General Hospital of PLA, Beijing 100853, China.
Hong RenThe Chinese PLA Medical School, Beijing 100853, China.
Juntang GuoThe First Medical Center, Department of Thoracic Surgery, Chinese General Hospital of PLA, Beijing 100853, China.

Funding

Hainan Province Health and Wellness Industry Research Project 22A200353
6 · The paper itself

Abstract

backgroundMediastinal benign teratoma is rare, with surgery being the only effective treatment. Few studies reported the surgical outcomes of resecting mediastinal benign teratomas via the subxiphoid approach by thoracoscopy. This study retrospectively compares the subxiphoid with other surgical approaches, aiming to assess the safety and feasibility of this technique.

methodsWe retrospectively analysed the clinical data of 159 patients with pathologically confirmed mediastinal benign teratomas who underwent surgery in 5 hospitals from July 2014 to June 2024. Various parameters of the subxiphoid approach were compared with those of other surgical methods.

resultsThe surgical approaches included median sternotomy in 26 cases, lateral thoracotomy in 14 cases, lateral thoracoscopic surgery in 80 cases, subxiphoid thoracoscopic surgery in 26 cases, and robotic surgery in 13 cases. For patients who underwent the subxiphoid approach, the median surgery time was 80 min (70, 90), the median intraoperative blood loss was 20 mL (10, 20), the median postoperative drainage volume was 200 mL (0, 350), and the median time to drain removal was 3 days (0, 3). Complete tumour resection was achieved in all 26 patients (100%). The subxiphoid approach showed advantages in the aforementioned aspects compared to other surgical methods.

conclusionsThe subxiphoid and subcostal arch approach is a safe and feasible surgical technique for benign anterior mediastinal teratoma, with a potentially faster postoperative recovery and less cost. It is a valuable alternative to conventional median sternotomy, lateral thoracotomy, and lateral thoracoscopic surgery in resection of anterior mediastinal teratoma.

Indexed as

Mediastinal NeoplasmsTeratomaThoracoscopyAdolescentAdultAgedChildFeasibility StudiesFemaleHumansMaleMiddle AgedOperative TimeRetrospective StudiesTreatment OutcomeYoung Adultanterior mediastinal tumoursubxiphoidteratomathoracoscopic surgery

Identifiers

PMID40758465
PMCPMC12343096

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.