Evidence map›Paper›PMID 40758191›Full record

ArticleJournal of cancer research and clinical oncology2025

Early versus delayed postoperative extubation after elective neurosurgical treatment of brain metastasis.

Logman Khalafov, T Lampmann, M Hamed, J Dittmer, I Maiseyeu, H Alenezi, M Jaber, H Asoglu, M Thudium, F Lehmann and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cancer research and clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Logman KhalafovDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany. logman.khalafov@ukbonn.de.
T LampmannDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany.
M HamedDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany.
J DittmerDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany.
I MaiseyeuDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany.
H AleneziDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany.
M JaberDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany.
H AsogluDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany.
M ThudiumDepartment of Anesthesiology, University Hospital Bonn, Bonn, Germany.
F LehmannDepartment of Anesthesiology, University Hospital Bonn, Bonn, Germany.
S EhrentrautDepartment of Anesthesiology, University Hospital Bonn, Bonn, Germany.
J PothDepartment of Anesthesiology, University Hospital Bonn, Bonn, Germany.
H VatterDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany.
M SchneiderDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany.
M BanatDepartment of Neurosurgery, University Hospital Bonn, Venusberg Campus 1, Building 81, 53127, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIt is generally assumed that early extubation after elective neurosurgical treatment of brain metastases (BMs) is associated with a lower rate of adverse events (AE), such as an increased rate of respiratory infections. The aim of this study is to investigate to what extent this association holds for the patient cohorts of our clinic who underwent elective intracranial surgery and whether in our experience early extubation (EE) was inferior to delayed extubation (DE). MATERIAL AND

methodsBetween 2018 and 2020, 190 patients were surgically treated for BM in the authors' neurosurgery department. Early extubation was defined as extubation immediately after surgery in the recovery room. The DE group was electively extubated after surgery in the intensive care unit. We analyzed demographic data, ASA status, blood loss, comorbidities, duration of surgery, blood transfusion, length of hospital stay, surgical-related complications and adverse events.

resultsA total of 65 patients (34.2%) were extubated early. In the remaining 65.8% of patients extubation was delayed. In the univariate analysis, no statistical significance was found between the two groups, particularly with regard to complications. The only relevant difference was in the DE group, who had greater transfusion requirements (p = 0.037). The DE group showed more AE, but this was not significant in the multivariate analysis.

conclusionsOur data demonstrate that early extubation was justifiable and safe for our patients. Early extubation in the recovery room did not pose a risk of re-intubation immediately after elective neurosurgical resection of a brain metastasis.

Indexed as

Airway ExtubationBrain NeoplasmsElective Surgical ProceduresNeurosurgical ProceduresAdultAgedFemaleHumansLength of StayMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTime FactorsBrain metastasisDelayed extubationEarly extubationIntensive care unit

Identifiers

PMID40758191
PMCPMC12321737

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.