Evidence map›Paper›PMID 40758183›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Long-term trends in the burden of fracture of vertebral column in China: a comprehensive analysis from 1990 to 2021 based on the global burden of disease study 2021.

Yu Lin, Min Chen, Shuting Liu, Zhouwei Zhan

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu LinDepartment of Orthopedics, Fujian Medical University Union Hospital, Fujian, 350001, Fuzhou, China.
Min ChenDepartment of Orthopedics, Fujian Medical University Union Hospital, Fujian, 350001, Fuzhou, China.
Shuting LiuHealth Management Center, The First Affiliated Hospital of Fujian Medical University, Fujian, 350001, Fuzhou, China. 95507662@qq.com.
Zhouwei ZhanDepartment of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fujian, 350014, Fuzhou, China. fjmuzzw@126.com.

Funding

Joint Funds for the innovation of science and Technology, Fujian province 2024Y9243Startup Fund for scientific research, Fujian Medical University 2021QH1040
6 · The paper itself

Abstract

backgroundFracture of vertebral column (FVC) is a major public health problem, but the epidemiological investigation of FVC based on large population in China is still limited. This study aims to comprehensively analyze the disease burden of FVC in China from 1990 to 2021, so as to provide insights for public health policies and intervention measures.

methodsBased on the Global Burden of Disease (GBD) database (1990-2021), the incidence, prevalence, and years lived with disability (YLDs) of FVC were evaluated. Joinpoint regression analysis was used to identify the significant change points of the trends. The age-period-cohort model was applied to analyze the age, period, and birth cohort effects. Decomposition analysis was conducted to quantify the contributions of population growth, aging, and epidemiological changes to the disease burden.

resultsIn 2021, FVC had a significant impact on the health of the Chinese population, with a total of 1,194,465 cases reported. The incidence, prevalence, and YLDs for males was higher than those for females. From 1990 to 2021, the age standardized incidence rate (ASIR), age standardized prevalence rate (ASPR) and YLDs of FVC in China showed an upward trend, especially among the elderly population. In contrast, the global trend showed a decrease in ASIR, ASPR, and YLDs rate. Joinpoint regression analysis showed that the ASIR, ASPR, and YLDs of FVC in China increased significantly from 2011 to 2021. Decomposition analysis indicated that population growth and epidemiological changes were the main factors for the increasing burden of FVC. Etiological analysis showed that unintentional injuries and traffic accidents were the main causes of FVC in China.

conclusionFVC constitutes a significant health burden in China, especially among the elderly and male populations. These findings highlight the need to develop targeted public health policies and intervention measures, such as strengthening osteoporosis management and transportation safety, for decreasing disease burden of FVC.

Indexed as

Global Burden of DiseaseSpinal FracturesAdolescentAdultAgedAged, 80 and overChildChild, PreschoolChinaFemaleHumansIncidenceInfantMaleMiddle AgedPrevalenceAging populationChinaEpidemiological trendsFracture of vertebral columnGlobal burden of disease.Sex disparities

Identifiers

PMID40758183

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.