Evidence map›Paper›PMID 40758115›Full record

ArticleAnnals of African medicine2025

Demystify Carbapenem-resistant Acinetobacter baumannii Pneumonia Burden: 2-Year Cohort Study.

Alfian Nur Rosyid, Pepy Dwi Endraswari, Firman Setiawan, Yessy Puspitasari, Tri Pudy Asmarawati, Brian Eka Rachman, Arina Dery Puspitasari, Ahmad Mufid Sultoni, Prastuti Asta Wulaningrum

Abstract readClinical Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of African medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alfian Nur RosyidDepartment of Pulmonology and Respiratory Medicine, Universitas Airlangga Hospital, Surabaya, Indonesia.
Pepy Dwi EndraswariDepartment of Clinical Microbiology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
Firman SetiawanDepartment of Clinical Microbiology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
Yessy PuspitasariYannas Husada Health Vocational School, Bangkalan, Indonesia.
Tri Pudy AsmarawatiFaculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Brian Eka RachmanFaculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Arina Dery PuspitasariDepartment of Clinical Pathology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
Ahmad Mufid SultoniDepartment of Internal Medicine, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
Prastuti Asta WulaningrumDepartment of Pulmonology and Respiratory Medicine, Universitas Airlangga Hospital, Surabaya, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe World Health Organization has identified carbapenem-resistant Acinetobacter baumannii (CRAB) infections as the most important pathogens for which new antibiotics must be developed immediately. Therefore, this study aimed to analyze the comparison of epidemiology, microbial pattern, and antibiotic resistance in CRAB and carbapenem-sensitive A . baumannii (CSAB).

methodsA retrospective cohort study was used, with community-acquired pneumonia with A . baumannii bacterial culture results. Data were obtained from the patient's medical record and the results of antibiotic sensitivity testing with the culture method by planting sputum on blood agar and MacConkey medium for 24 h.

resultsA total of 50 patients, CRAB ( n = 26) and CSAB ( n = 24), found that the average gender was male in CRAB compared to CSAB (69.2% vs. 48.2%). Complications of respiratory failure, sepsis, and acute respiratory distress syndrome were higher in CRAB compared to CSAB (30.8% vs. 20.8%, 46.2% vs. 25%, and 2% vs. 0%). The mortality rate in the CRAB group was 53.8% vs. CSAB 12.5%. The mean length of stay (LOS) in CRAB was 17.92, while CSAB was 11.00. The mean cost of hospitalization in CRAB was higher than CSAB ($6993.0615 vs. $3263.7375). The mean neutrophil-to-lymphocyte ratio value in the CRAB group was 20.4, while in CSAB was 10.6.

conclusionsThe results indicated that CRAB infection carries a greater burden in terms of cost of treatment, mortality, LOS, and more serious complications, compared to CSAB infection.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsCarbapenemsPneumonia, BacterialAdultAgedCohort StudiesCommunity-Acquired InfectionsDrug Resistance, BacterialFemaleHumansLength of StayMaleMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial AgentsCarbapenemsCommunity-acquired pneumoniaPneumonie acquise en communauté

Identifiers

PMID40758115
PMCPMC12588436

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