Evidence map›Paper›PMID 40757769›Full record

ArticleACS synthetic biology2025

Improving the Transformation Efficiency of

Andrew Hren, William G Alexander, Joshua P Abraham, Melissa P Tumen-Velasquez, Michael Melesse Vergara, Adam M Guss, Brian F Pfleger, Jerome M Fox, Carrie A Eckert

Abstract read
In one paragraph

Article in ACS synthetic biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrew HrenDepartment of Chemical and Biological Engineering, University of Colorado, Boulder, Colorado 80304, United States.
William G AlexanderBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States.ORCID 0000-0003-4212-6392
Joshua P AbrahamDepartment of Chemical and Biological Engineering, University of Wisconsin, Madison, Wisconsin 53706, United States.ORCID 0000-0002-1599-2183
Melissa P Tumen-VelasquezBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States.
Michael Melesse VergaraBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States.
Adam M GussBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States.
Brian F PflegerDepartment of Chemical and Biological Engineering, University of Wisconsin, Madison, Wisconsin 53706, United States.
Jerome M FoxDepartment of Chemical and Biological Engineering, University of Colorado, Boulder, Colorado 80304, United States.ORCID 0000-0002-3739-1899
Carrie A EckertBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States.ORCID 0000-0003-4201-2926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyanobacteria are promising microbial platforms for a diverse set of biotechnology applications, from living materials to photosynthetic chemical production, but are less well characterized than commonly engineered microbes such as

Indexed as

DNA, BacterialDNA MethylationSynechococcusTransformation, BacterialEscherichia coliGene EditingMetabolic EngineeringMethyltransferasesDNA, BacterialMethyltransferasescyanobacteriaDNA methylationgenetic engineeringrestriction modificationtransformation efficiency

Identifiers

PMID40757769
PMCPMC12362590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.