ArticleArchives of rheumatology2025
Serum Catestatin Levels and Its Relationship with Disease Activity in Patients with Ankylosing Spondylitis.
Article in Archives of rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Serum Catestatin Levels and Their Association with Pain Severity in Fibromyalgia Syndrome: A Cross-Sectional Case-Control Study.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/Aims: Catestatin (CST) is a bioactive peptide with wellestablished cardiovascular roles, including anti-inflammatory and metabolic effects. This study aimed to compare the serum CST levels in patients with ankylosing spondylitis (AS) and healthy control subjects. Materials and Methods: This cross-sectional study included 95 patients with AS who met the Assessment of SpondyloArthritis International Society classification criteria for AS and 85 healthy individuals. Demographic, clinical, and laboratory parameters were recorded. Serum CST levels were measured by commercially available enzyme-linked immunosorbent assay kits. Results: Median serum CST levels were significantly lower in patients with AS compared to the control group (2.57 [1.74-4.58] vs 9.4 [3.55-26.6] ng/mL, P < .001). Catestatin levels were lower in the active AS group than in the inactive AS and control groups (P < .05). Significant negative correlations were found between CST and age, ankylosing spondylitis disease activity score-C-reactive protein (ASDAS-CRP), and C-reactive protein. Multiple linear regression analysis demonstrated that serum CST levels were significantly associated with the ASDAS-CRP group variable after model adjustment for sex, age, body mass index, HLA-B27 status, disease duration, and medications. Conclusion: These findings suggest that CST may play a role in the complex pathophysiology of AS. However, future multicenter longitudinal studies are necessary to further elucidate the relationship between CST and AS.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.