Evidence map›Paper›PMID 40757743›Full record

ArticleJournal of investigative medicine high impact case reports

A Rare Case of Primary Small Cell Carcinoma of the Esophagus.

Jiya Mulayamkuzhiyil, Justeena Joseph, Anchita Agrawal, Tommy Ojukwu Perdomo, Sanjeev Jain

Abstract readCase Reports
In one paragraph

Article in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiya MulayamkuzhiyilNYU Langone Hospital-Suffolk, Patchogue, USA.ORCID 0000-0003-3032-9328
Justeena JosephNYU Langone Hospital-Suffolk, Patchogue, USA.
Anchita AgrawalJericho High School, Jericho, NY, USA.ORCID 0009-0002-5930-8803
Tommy Ojukwu PerdomoNYU Langone Hospital-Suffolk, Patchogue, USA.ORCID 0009-0001-8076-3571
Sanjeev JainNYU Langone Hospital-Suffolk, Patchogue, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small cell carcinoma of the esophagus is a rare and aggressive variant of esophageal cancer. We report a case of a 69-year-old female who presented with dysphagia to solid food for 6 months and underwent esophagogastroduodenoscopy, which revealed an ulcerated mass in the proximal esophagus. Biopsy findings were consistent with esophageal small cell cancer. The patient was found to have distant metastasis to the gastric lymph nodes on staging studies. She was treated with chemotherapy, resulting in initial disease resolution, but 4 years later, she presented with metastatic disease to the lungs and brain. This case underscores the need to establish treatment guidelines for this malignancy with a poor prognosis, given the paucity of randomized clinical trials.

Indexed as

Carcinoma, Small CellEsophageal NeoplasmsAgedBrain NeoplasmsDeglutition DisordersEndoscopy, Digestive SystemFemaleHumansLung NeoplasmsLymphatic Metastasishematology oncologypathology

Identifiers

PMID40757743
PMCPMC12322346

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.