Evidence map›Paper›PMID 40757654›Full record

ArticlePrion2025

Canadian 2021 H-type Bovine Spongiform Encephalopathy case associated with a novel E211K polymorphism in prion protein gene.

Waqas Tahir, Sandor Dudas, Renee Anderson, Jianmin Yang, Sarah Bogart, Kristina Santiago-Mateo, Yuanmu Fang, Roberta Quaghebeur

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Prion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Waqas TahirCanadian and WOAH Reference Laboratory for BSE, Canadian Food Inspection Agency, National Centre for Animal Diseases, Lethbridge, Canada.
Sandor DudasCanadian and WOAH Reference Laboratory for BSE, Canadian Food Inspection Agency, National Centre for Animal Diseases, Lethbridge, Canada.
Renee AndersonCanadian and WOAH Reference Laboratory for BSE, Canadian Food Inspection Agency, National Centre for Animal Diseases, Lethbridge, Canada.
Jianmin YangCanadian and WOAH Reference Laboratory for BSE, Canadian Food Inspection Agency, National Centre for Animal Diseases, Lethbridge, Canada.
Sarah BogartCanadian and WOAH Reference Laboratory for BSE, Canadian Food Inspection Agency, National Centre for Animal Diseases, Lethbridge, Canada.
Kristina Santiago-MateoCanadian and WOAH Reference Laboratory for BSE, Canadian Food Inspection Agency, National Centre for Animal Diseases, Lethbridge, Canada.
Yuanmu FangCanadian and WOAH Reference Laboratory for BSE, Canadian Food Inspection Agency, National Centre for Animal Diseases, Lethbridge, Canada.
Roberta QuaghebeurCanadian and WOAH Reference Laboratory for BSE, Canadian Food Inspection Agency, National Centre for Animal Diseases, Lethbridge, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine Spongiform Encephalopathy (BSE) is a fatal neurodegenerative disease in cattle which can be either classical BSE (C-BSE) or atypical BSE (including H-BSE and L-BSE). Here, we report the results of our analyses of an H-BSE case found in Canada in 2021, indicating restriction of the pathological agent (PrP

Indexed as

Encephalopathy, Bovine SpongiformPolymorphism, GeneticPrion ProteinsAnimalsCanadaCattlePrion ProteinsAtypical BSEBovine Spongiform Encephalopathycentral nervous systemE211K mutationprion diseasesprion protein genesynonymous mutation

Identifiers

PMID40757654
PMCPMC12323412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.