ArticleEmergency medicine Australasia : EMA2025
Prevalence of GHB-Related Presentations to a Metropolitan Emergency Department in Melbourne.
Article in Emergency medicine Australasia : EMA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Toxicological and Clinical Characteristics of Fatal Cases in the Emerging Drugs Network of Australia-Victoria (EDNAV) Clinical Registry 2020-2025.Emergency medicine Australasia : EMA · 2026Observational
- Prevalence of GHB-Related Presentations to a Metropolitan Emergency Department in Melbourne.Emergency medicine Australasia : EMA · 2025Article
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10 authors.
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Abstract
introductionGamma-hydroxybutyrate (GHB) is a commonly used recreational substance. It has a narrow therapeutic index. The management of GHB overdose in the emergency department (ED) is labour and resource intensive. This study aims to provide a comprehensive analysis of GHB presentations at one of Victoria's largest tertiary hospitals. METHODOLOGY: We conducted a retrospective study on GHB-related ED presentations between 2014 and 2024 and reported a case series of admissions to the Intensive Care Unit (ICU). For ICU admitted patients, confirmation of GHB presence in blood was collected through the Emerging Drug Network of Australia-Victoria (EDNAV) study.
resultsWe recorded 2631 cases of GHB-related presentations. The median age was 29 years and 42.3% of cases were female. The presentations of individuals under 25 years of age declined from 61.4% to 14.0%. The majority of patients (81.0%) were brought in by ambulance, with 12.5% accompanied by police. Most patients (93.9%) were managed and discharged from the ED or Short Stay Unit. Only a small proportion of patients (108, 4.1%) required ICU admission. The median stay in the ICU was 2 days. 88.7% of cases admitted to the ICU required intubation. Eight ICU-admitted patients, recruited for the EDNAV study, had a confirmed presence of GHB and other co-ingestions. DISCUSSION: Our study showed a significant increase in GHB-related presentations to our ED. There has been a notable shift in the demographics of patients presenting to EDs with GHB-related issues. GHB use poses a significant impact on EDs and intensive care services.
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