SynthesisBiomarkers in medicine2025
Predictive value of NLR for the occurrence and clinical outcomes of hypertension: a systematic review and meta-analysis.
Synthesis in Biomarkers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between neutrophil-to-lymphocyte ratio and the prognosis of patients with rheumatoid arthritis: a meta-analysis.Frontiers in immunology · 2026Pooled it
- Association of Inflammatory-Hematological Biomarkers with Hypertension and Related Comorbidities.Journal of clinical medicine · 2026Article
- The Association Between Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios and Anemia in Adults with Hypertension in Southwestern Uganda: A Cross-Sectional Study.Journal of blood medicine · 2026Article
- Neutrophil-lymphocyte ratio and subclinical atherosclerosis in essential hypertensive patients.Frontiers in cardiovascular medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThis paper aims to perform a meta-analysis to provide the most updated and comprehensive evidence on the link between neutrophil-lymphocyte ratio (NLR) and the development and prognosis of hypertension. MATERIALS &
methodsCochrane Library, PubMed, Embase, and Web of Science were thoroughly searched for studies published from the inception of the databases up to 4 May 2024 using the keywords "Lymphocytes," "Neutrophils," "Ratio," and "Hypertension." The odds ratios (OR) and 95% confidence intervals (CI) were extracted for random-effects meta-analysis. We employed Egger's test to check publication bias, sensitivity analyses to identify studies that significantly impacted the meta-analysis results, and subgroup analyses to ascertain the source of heterogeneity.
results10 articles involving 78,194 patients were enrolled. The pooled data indicated that NLR was a significant predictor of hypertension risk (OR = 1.11, 95% CI = 1.05-1.17,
conclusionNLR is a reliable and valuable biomarker for predicting both the risk of hypertension and outcomes in hypertensive patients.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.