ArticleACG case reports journal2025
Successful Use of Corticosteroids to Accelerate Recovery in Severe Autoimmune-like Hepatitis From Isoniazid.
Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Immune-Related Hepatotoxicity After Atezolizumab and Isoniazid.Infectious diseases & clinical microbiology · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drug-induced autoimmune-like hepatitis represents a distinct phenotype of drug-induced liver injury characterized by clinical, biochemical, and/or histological features resembling autoimmune hepatitis. We present a case of severe Isoniazid (INH) -induced drug-induced autoimmune-like hepatitis in a 62-year-old man with a dramatic response to corticosteroid therapy after INH discontinuation alone proved insufficient. Initial laboratory tests showed markedly elevated transaminases and profound hyperbilirubinemia. Despite INH discontinuation, his clinical condition did not improve. Liver biopsy revealed severe acute hepatitis with interface hepatitis, lymphoplasmacytic infiltration, and multiple foci of lobular confluent necrosis. Prednisone therapy led to rapid clinical improvement and normalization of liver biochemistries over 3 months.
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