Evidence map›Paper›PMID 40757075›Full record

ArticleACG case reports journal2025

An Unexpected Culprit: Fatal Gastrointestinal Hemorrhage due to Duodenal Histoplasmosis in a Patient With End-Stage Renal Disease.

Vanya Rai, Rohit Goyal, Aditya Vyas, Karan Sachdeva, Kshitij Arora, Hassan Zia

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vanya RaiDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.
Rohit GoyalDepartment of Internal Medicine, Louisiana State University Health Shreveport, Shreveport, LA.ORCID https://orcid.org/0000-0002-9529-5096
Aditya VyasDivision of Gastroenterology and Hepatology, Louisiana State University Health Shreveport, Shreveport, LA.
Karan SachdevaDepartment of Internal Medicine, Louisiana State University Health Shreveport, Shreveport, LA.
Kshitij AroraDepartment of Pathology, Louisiana State University Health Shreveport, Shreveport, LA.
Hassan ZiaDivision of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histoplasmosis has a wide spectrum of presentations ranging from mild pulmonary disease to a more widespread infection leading to disseminated histoplasmosis. Gastrointestinal histoplasmosis is a rare form of disseminated histoplasmosis that most commonly causes nonspecific symptoms and rarely presents with serious symptoms. Duodenal involvement is further rare but can cause ulcerated lesions leading to upper gastrointestinal bleed. The potential for a nonspecific initial presentation quickly progressing to a fatal upper gastrointestinal bleed makes it important to keep Gastrointestinal histoplasmosis in our list of differentials, as timely initiation of appropriate antifungal therapy can significantly reduce the risk of severe complications and mortality.

Indexed as

disseminated histoplasmosisduodenal ulcergastrointestinal histoplasmosismelenaupper gastrointestinal bleed

Identifiers

PMID40757075
PMCPMC12316352

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.