ArticleJournal of maxillofacial and oral surgery2025
A Comparative Evaluation of Platelet-Rich Fibrin and Platelet-Rich Fibrin Matrix in Terms of pH, Antimicrobial Potential and Histological Presentation: An In vitro Study.
Article in Journal of maxillofacial and oral surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Influence of Local Anesthesia Techniques on the Microstructural Integrity of Dental Injection Needles: A Field Emission Scanning Electron Microscopy Analysis.Bioengineering (Basel, Switzerland) · 2026Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: In recent times, autologous platelet concentrates (APCs) like platelet-rich fibrin (PRF) and platelet-rich fibrin matrix (PRFM) are utilized broadly to promote soft and hard tissue regeneration. The aim of the study was to evaluate PRF and PRFM in terms of pH changes (over a five-day period), antimicrobial potential and histological presentation using light microscopy and field-emission scanning electron microscopic analysis (FESEM). Materials and Methods: A prospective comparative in vitro study was conducted in which PRF and PRFM samples were prepared from 21 healthy volunteers and a comparative evaluation for the parameters was carried out. Results: A statistically significant difference was found between PRF and PRFM in terms of pH over a five-day period; antimicrobial efficacy at 48 h; average thickness of fibrin; distribution of platelets and leucocytes entrapped in fibrin matrix. Conclusion: From our research study, it can be concluded that PRF when compared to PRFM showed abundant entrapment of platelets and leucocytes enmeshed in the 3-D fibrin matrix which is responsible for its better antimicrobial property. PRF also showed increasing acidity over days which accelerates the process of wound healing at the injury site. Thus, PRF is a better autologous platelet concentrate than PRFM.
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