ArticleJournal of maxillofacial and oral surgery2025
Multidisciplinary Management of Aggressive Giant Cell Tumour of the Mandible Using Denosumab, Virtual Surgical Planning, and Patient-Specific Implants: A Case Report with Myasthenia Gravis Considerations.
Article in Journal of maxillofacial and oral surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Introduction: This report describes the management of an aggressive mandibular giant cell tumour (GCT) in a 59-year-old male with comorbid myasthenia gravis (MG). Case Report: A multidisciplinary approach incorporating neoadjuvant Denosumab, virtual surgical planning, and patient-specific implants enabled precise tumour resection and reconstruction while minimising anaesthesia-related risks. Results and Conclusion: The use of advanced techniques significantly reduced surgical time and enhanced functional and aesthetic outcomes. This case highlights the feasibility and effectiveness of integrating modern chemotherapeutics and digital technologies in surgically managing complex maxillofacial tumours, particularly in patients with high perioperative risk due to systemic conditions like MG.
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