Evidence map›Paper›PMID 40756887›Full record

ReviewJournal of the Royal Society of New Zealand2025

Distinguishing chronic pain from mechanical factors in chronic TMD: a narrative review.

Blake Moore, Guangzhao Guan, Brian Whitley, Li Mei, Ajith D Polonowita

Abstract readReview
In one paragraph

Review in Journal of the Royal Society of New Zealand, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Blake MooreDepartment of Oral Diagnostic and Surgical Sciences, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.
Guangzhao GuanDepartment of Oral Diagnostic and Surgical Sciences, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.
Brian WhitleyConsultant Oral & Maxillofacial Surgeon, Private Practice, Hamilton, New Zealand.
Li MeiDepartment of Oral Sciences, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.
Ajith D PolonowitaDepartment of Oral Diagnostic and Surgical Sciences, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The International Classification of Diseases-11 (ICD-11) defines chronic pain conditions as those that lack identifiable underlying pathology at the site of pain. In parallel, the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) system was developed as a comprehensive framework for diagnosing and managing conditions previously classified under the broader category of temporomandibular disorders (TMD). While the DC/TMD system provides a structured and clinically useful approach, it does not fully distinguish between pain-related disorders and mechanical dysfunction associated with TMD. Specifically, mechanical temporomandibular joint (TMJ) conditions, as described in the DC/TMD, are distinct from chronic pain present in chronic TMD (cTMD). These mechanical issues may or may not involve chronic pain, and despite often coexisting with chronic facial pain, they represent separate diagnostic entities that necessitate individualised management strategies. This differentiation is essential for accurate diagnosis and effective treatment of chronic TMD patients. This review provides a comprehensive analysis of cTMD, synthesising evidence from genotyping studies, systemic inflammation, immune dysregulation, endocrine disturbances, advanced imaging, and the biopsychosocial model. By integrating these diverse perspectives, it explores the complex interplay between genetic predisposition, anatomical factors, systemic inflammation, immune and endocrine imbalances, and biopsychosocial influences in cTMD.

Indexed as

chronic painchronic TMDDC/TMDTMDTMJ

Identifiers

PMID40756887
PMCPMC12315194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.