Evidence map›Paper›PMID 40756817›Full record

SynthesisFrontiers in artificial intelligence2025

The application of random forest-based models in prognostication of gastrointestinal tract malignancies: a systematic review.

Zhina Mohamadi, Ahmad Shafizadeh, Yasaman Aliyan, Seyedeh Fatemeh Shayesteh, Parsa Goudarzi, Alireza Khodabandeh, Amirali Vaghari, Helma Ashrafi, Omid Bahrami, Armin ZarinKhat and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhina Mohamadi *Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Ahmad Shafizadeh *Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Yasaman Aliyan *Faculty of Medicine, Tehran Medical Science Islamic Azad University, Tehran, Iran.
Seyedeh Fatemeh ShayestehFaculty of Allied Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Parsa GoudarziFaculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Alireza KhodabandehStudent Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.
Amirali VaghariFaculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Helma AshrafiFaculty of Medicine, Shahroud University of Medical Sciences, Semnan, Iran.
Omid BahramiSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Armin ZarinKhatFaculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Yalda KhodabandehFaculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Kimia PouyanFaculty of Medicine, Ahvaz University of Medical Sciences, Ahvaz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Malignancies of the GI tract account for one-third of cancer-related deaths globally and more than 25% of all cancer diagnoses. The rising prevalence of GI tract malignancies and the shortcomings of existing treatment approaches highlight the need for better predictive prediction models. RF's machine-learning method can predict cancers by using numerous decision trees to locate, classify, and forecast data. This systematic study aims to assess how well RF models predict the prognosis of GI tract malignancies. Methods: Following PRISMA criteria, we performed a systematic search in PubMed, Scopus, Google Scholar, and Web of Science until May 28, 2024. Studies used RF models to forecast the prognosis of GI tract malignancies, including esophageal, gastric, and colorectal cancers. The QUIPS approach was used to evaluate the quality of the included studies. Results: Out of 1846 records, 86 studies met inclusion requirements; eight were disqualified. Numerous studies showed that when combining clinical, genetic, and pathological data, RF models were very accurate and dependable in predicting the prognosis of GI tract malignancies, responses, recurrence, survival rates, and metastatic risks, distinguishing between operable and inoperable tumors, and patient outcomes. RF models outperformed conventional prognostic techniques in terms of accuracy; several research studies reported prediction accuracies of over 80% in survival rate estimates. Conclusion: RF models, in terms of accuracy, performed better than the conventional approaches and provided better capabilities for clinical decision-making. Such models can increase the life quality and survival of patients by personalizing their treatment regimens for cancers of the GI tract. These models can, in a significant manner, raise patients' survival and quality of life through hastening clinical decision-making and providing personalized treatment options.

Indexed as

GI tract cancersmalignancyprognoseprognosticationrandom forest

Identifiers

PMID40756817
PMCPMC12315591

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.