ArticleInfection and drug resistance2025
Impact of Pharmacist-Led Anti-Infective Consultations on Therapeutic Outcomes: A Retrospective Cohort Study in a Tertiary Hospital.
Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- High-magnification inpatient cases under DIP payment reform: prevalence, cost burden, and risk factors in an NHC-administered hospital in China.Frontiers in public health · 2026Observational
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the clinical and economic impact of pharmacist-led anti-infective consultations in a Chinese tertiary hospital under diagnosis-related group (DRG) payment reforms. Methods: This retrospective cohort study analyzed inpatients receiving pharmacist-led anti-infective consultations from Tongde Hospital of Zhejiang Province in 2024. Patients were stratified into adherence and non-adherence groups based on clinicians' implementation of pharmacist recommendations. Outcomes included clinical response rates, adverse drug reactions (ADRs), 14-day mortality, total costs of antimicrobial therapy and total hospitalization costs. Results: In this study, clinical pharmacists conducted 498 anti-infective therapy consultations for 313 patients, with 82.13% (409/498) of their recommendations being accepted by clinicians. The results demonstrated that adherence to clinical pharmacist recommendations significantly enhanced the clinical response rate (81.99% vs 38.46%, p < 0.05), decreased the incidence of adverse drug reactions (4.21% vs 13.46%, p< 0.05), and reduced 14-day mortality (5.75% vs 17.31%, p< 0.05). Furthermore, adherence led to a 69% reduction in the average cost of antimicrobial therapy ($1830.79 vs $5983.14, p< 0.05) and a 58% decrease in the average total cost of hospitalization ($15,306.17 vs $36,799.11, p< 0.05). Conclusion: Pharmacist-led anti-infective consultations demonstrate efficacy in enhancing infection treatment outcomes and curbing antimicrobial expenditures, providing actionable evidence for scaling antimicrobial stewardship programs in one DRG-based hospital in China.
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