ArticleOpen forum infectious diseases2025
Limited Diagnostic and Therapeutic Value of Chest X-Rays in Hematological Patients With Febrile Neutropenia.
Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: In hematological patients with febrile neutropenia, chest X-rays are frequently performed to exclude possible pulmonary infections. However, the diagnostic and therapeutic value of this imaging remains unclear. Methods: We conducted a retrospective observational cohort study over a 2-year period, examining episodes of febrile neutropenia in adult patients treated with myelosuppressive chemotherapy. Febrile episodes were categorized based on the presence (group A) or absence (group B) of respiratory symptoms. We assessed the frequency of abnormal chest X-rays and chest computed tomography (CT) scans and their impact on antimicrobial treatment decisions. Results: Of the 412 febrile episodes in 259 patients, 41.4% in group A and 16.1% in group B had an abnormal chest X-ray ( Conclusions: Chest X-rays rarely influence antibiotic treatment decisions in febrile neutropenia and can probably be safely omitted, especially in patients without respiratory symptoms.
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