ArticleFrontiers in cardiovascular medicine2025
Clinical characteristics and prognosis analysis of patients with myocardial infarction with non-obstructive coronary arteries in the Qinghai-Tibet plateau region.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the etiology and clinical characteristics of patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) in the Qinghai-Tibet Plateau region. Methods: A retrospective analysis was conducted on 82 acute myocardial infarction (AMI) patients who underwent coronary angiography in the Department of Cardiology at Shigatse People's Hospital between December 2020 and December 2021. Patients were divided into two groups based on the results of coronary angiography: the myocardial infarction associated with obstructive coronary artery disease (MI-CAD group, Results: Among the 15 MINOCA patients, the primary etiologies included: coronary plaque rupture in 2 cases (13.33%), coronary artery spasm in 2 cases (13.33%), coronary thrombosis or embolism in 1 case (6.67%), type 2 AMI in 1 case (6.67%), unrecognized myocarditis in 3 cases (20%), and other unknown causes in 6 cases. Compared with the MI-CAD group, MINOCA patients had a significantly lower BMI ( Conclusion: Due to factors such as hypoxic environments and different lifestyles, MINOCA in the plateau region exhibits characteristics distinct from those observed in low-altitude regions. Enhanced follow-up of these patients is recommended. Further exploration of the mechanisms underlying MINOCA in high-altitude environments is warranted to provide a basis for disease prevention and the development of individualized treatment strategies.
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