Evidence map›Paper›PMID 40756420›Full record

ArticleJournal of inflammation research2025

Correlation Between Peripheral Blood Immune Cell Distribution and Disease Severity and Prognosis in Multiple Sclerosis Patients.

Pen-Ju Liu, Peng Yuan, Shui-Ping Liu

Abstract read
In one paragraph

Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pen-Ju LiuDepartment of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.
Peng YuanDepartment of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.
Shui-Ping LiuDepartment of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to examine the relationship between peripheral blood immune cell distribution patterns and both disease severity and prognosis in patients with multiple sclerosis (MS). Methods: We conducted a retrospective analysis of clinical data from MS patients admitted to the Neurology Department of our Hospital between March 2020 and April 2024. Data collected included gender, age (years), disease duration (months), clinical manifestations, and results from blood and cerebrospinal fluid (CSF) tests. Disease severity and prognosis were assessed using the Expanded Disability Status Scale (EDSS) and Multiple Sclerosis Functional Composite (MSFC). Spearman correlation and multivariate linear regression (adjusted for age, gender, disease duration, and MS subtype) were employed to evaluate associations. Results: Of the MS patients studied, 10.4% (n=7) exhibited abnormal CSF pressure. The mean peripheral blood leukocyte count was 6.69 ×10 Conclusion: In MS patients, peripheral blood immune cells are predominantly neutrophils and lymphocytes, with CD4

Indexed as

cerebrospinal fluidimmune cellslymphocytesmultiple sclerosis

Identifiers

PMID40756420
PMCPMC12315911

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.