Evidence map›Paper›PMID 40756063›Full record

ArticleIEEE journal of solid-state circuits2025

A Nonuniform Sampling Lifetime Estimation Technique for Luminescent Oxygen Measurements for Biomedical Applications.

Ian Costanzo, Devdip Sen, John McNeill, Ulkuhan Guler

Abstract read
In one paragraph

Article in IEEE journal of solid-state circuits, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ian CostanzoDepartment of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA 01609 USA.ORCID 0000-0002-1648-9205
Devdip SenDepartment of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA 01609 USA.ORCID 0000-0003-3201-424X
John McNeillDepartment of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA 01609 USA.ORCID 0000-0002-6731-9484
Ulkuhan GulerDepartment of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA 01609 USA.ORCID 0000-0002-4723-4424

Funding

SCH: A Novel Bias-mitigated Multimodal Oxygen MonitorR01HL172293 · NHLBI · WORCESTER POLYTECHNIC INSTITUTE · PI Ulkuhan Guler · 2023 to 2026
$1.1M
Computational Models for Smart CO2 MonitoringR21EB036329 · NIBIB · MICHIGAN STATE UNIVERSITY · PI GULER, ULKUHAN, UNLUTURK, BIGE DENIZ · 2024 to 2024
$374k
NHLBI NIH HHS R01 HL172293NIBIB NIH HHS R21 EB036329
6 · The paper itself

Abstract

This article presents a novel technique that is immune to offset, enabling precise determination of the lifetime of luminescent materials. The technique is specifically applied to measure transcutaneous oxygen, an indicator of oxygen that diffuses through the skin and reflects arterial oxygen levels. Unlike intensity-based measurements, lifetime-based luminescence measurements are superior because they decouple oxygen information from confounding factors. The technique presented in this work involves measuring the time difference between fixed-voltage steps to extract the time constant of a decaying exponential, which represents the lifetime of luminescence. We propose a novel switched-capacitor circuit that enables long integration times and prevents the front-end amplifier from saturating. The analog subsystem was realized in 180-nm CMOS technology via a transimpedance amplifier (TIA) with a gain bandwidth product of 10 MHz, a comparator, and a switched capacitor circuit. The measured mean error is as accurate as 1.9% without postprocessing. During a 130

Indexed as

Analog-to-digital converter (ADC)blood gaseslight-to-digital converter (LTC)luminescent measurementsnonuniform sampling (NUS)oxygen sensortranscutaneous sensing

Identifiers

PMID40756063
PMCPMC12313304

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.