ArticleJournal of Indian Association of Pediatric Surgeons
Predictive Value of Cortical Transit Time on Diuretic Renography in Determining the Need for Surgery and Evaluating the Postoperative Outcome in Ureteropelvic Junction Obstruction in Children: A Prospective Observational Study.
Article in Journal of Indian Association of Pediatric Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Ureteropelvic junction obstruction (UPJO) is the most common cause of antenatal hydronephrosis. Although the majority of them improve with time, none of the existing diagnostic modalities can accurately predict which hydronephrotic kidney is at the risk of progressive renal damage and will benefit from early surgery. Few authors have suggested that a delayed cortical transit time (CTT) on diuretic renography is a reliable prognostic factor for both the need for surgery and renal functional improvement after surgery. Methodology: We designed this prospective observational study on CTT in Results: We found a CTT of more than 210 s to be associated with a 95% sensitivity and 74% specificity for the requirement of surgery in children with unilateral UPJO. The limitation of our study was the small sample size ( Conclusion: The predictive value of CTT as a reliable and sensitive indicator of surgery and early recovery even after 3 months of surgery. CTT can be used to identify reliably those subset of patients with unilateral UPJO who will deteriorate irreversibly. We are proposing the cutoff value of CTT to be 210 s, unlike several previous researchers, who have found a cutoff value of 180 to be significant.
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