Evidence map›Paper›PMID 40755914›Full record

ArticleFrontiers in pediatrics2025

Case Report: Clinical, molecular, and functional characterization of autoimmune lymphoproliferative syndrome-a family study with a multimodal diagnosis.

Bruna Cândido Guido, Ricardo Camargo, Caroliny Victoria Dos Santos Silva, Anna Carolina Silva Dias, Robéria Mendonça de Pontes, Agenor de Castro Moreira Dos Santos Júnior, Raquel Alves Toscano, Fabíola Scancetti Tavares, Alexandre de Albuquerque Antunes, Karina Mescouto de Melo

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bruna Cândido GuidoLaboratório de Pesquisa Translacional, Hospital da Criança de Brasília José Alencar, Brasília, Distrito Federal, Brazil.
Ricardo CamargoLaboratório de Pesquisa Translacional, Hospital da Criança de Brasília José Alencar, Brasília, Distrito Federal, Brazil.
Caroliny Victoria Dos Santos SilvaLaboratório de Pesquisa Translacional, Hospital da Criança de Brasília José Alencar, Brasília, Distrito Federal, Brazil.
Anna Carolina Silva DiasLaboratório de Pesquisa Translacional, Hospital da Criança de Brasília José Alencar, Brasília, Distrito Federal, Brazil.
Robéria Mendonça de PontesLaboratório de Pesquisa Translacional, Hospital da Criança de Brasília José Alencar, Brasília, Distrito Federal, Brazil.
Agenor de Castro Moreira Dos Santos JúniorLaboratório de Pesquisa Translacional, Hospital da Criança de Brasília José Alencar, Brasília, Distrito Federal, Brazil.
Raquel Alves ToscanoLaboratório de Pesquisa Translacional, Hospital da Criança de Brasília José Alencar, Brasília, Distrito Federal, Brazil.
Fabíola Scancetti TavaresAllergy and Immunology Unit, Hospital da Criança de Brasília José Alencar, Brasília, Distrito Federal, Brazil.
Alexandre de Albuquerque AntunesLaboratório de Pesquisa Translacional, Hospital da Criança de Brasília José Alencar, Brasília, Distrito Federal, Brazil.
Karina Mescouto de MeloLaboratório de Pesquisa Translacional, Hospital da Criança de Brasília José Alencar, Brasília, Distrito Federal, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune Lymphoproliferative Syndrome (ALPS) is a rare immunological disorder caused by defective apoptosis, commonly due to pathogenic variants in the

Indexed as

apoptosis defectsautoimmune lymphoproliferative syndrome (ALPS)CASP10 variantdiagnosisFAS variantfunctional assayimmunophenotyping

Identifiers

PMID40755914
PMCPMC12313618

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.