ArticleCureus2025
Treatment of Acne Scar Contraction Using Autologous Cultured Epithelial Sheet Transplantation: A Report of Four Cases.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Efficacy and safety of autologous cell-based therapies for atrophic acne scar treatment: an updated systematic review and meta-analysis with in-depth methodological and clinical insights.Frontiers in cell and developmental biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acne vulgaris often results in disfigurement with scarring if early treatment is insufficient. In particular, tissue destruction due to infection of hair follicles leads to contracture. There are many treatments for acne scars and scar contracture, but therapy of scar contracture, especially ice pick-like scars or crater-shaped scars, is difficult. In this study, we attempted treatment with grafting of an autologous cultured epithelial sheet in four patients with acne vulgaris accompanied by scar contracture. As a result, not only was the scarring improved, but the skin texture was also improved in all cases three months after grafting. Excessive collagen synthesis during the healing process following tissue destruction induces scar contracture, but various proteases secreted by the grafted cultured epithelium are thought to metabolize this excess collagen, improving the scarring and skin texture. Autologous cultured epithelium grafting, which can be completed with a single treatment, may be an effective method for treating acne scars.
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Registered trials
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