Evidence map›Paper›PMID 40755574›Full record

ArticleCureus2025

A Case of Synchronous Bilateral Canalicular Adenoma and Polymorphous Adenocarcinoma of the Minor Salivary Glands of the Upper Lip.

Holly Boyes, Rahail Kumar, Mathew Alemkunnapuzha, Mohammed Anabtawi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Holly BoyesOral and Maxillofacial Surgery, Pinderfields General Hospital, Wakefield, GBR.
Rahail KumarOral and Maxillofacial Surgery, Leeds General Infirmary, Leeds, GBR.
Mathew AlemkunnapuzhaHistopathology, Pinderfields General Hospital, Wakefield, GBR.
Mohammed AnabtawiOral and Maxillofacial Surgery, Leeds General Infirmary, Leeds, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple salivary gland tumours can occur in both major and minor salivary glands. Its histology can be greatly varied and include pleomorphic adenoma, canalicular adenoma, mucoepidermoid carcinoma, or polymorphous adenocarcinoma, amongst other pathologies. A 76-year-old lady was referred on a two-week-wait pathway to our oral and maxillofacial surgery department complaining of a one-year history of painless lumps in her upper lip, which were gradually increasing in size. Examination in the clinic revealed four distinct lumps in the upper lip that were firm on palpation but mobile. Histopathological examination revealed the two medial lesions to be polymorphous adenocarcinomas and the two lateral lesions to be canalicular adenomas. Whilst our case represents uncommon pathologies, our patient's demographics are typical of others in the literature. This highlights the importance of adequate biopsies to gain a representative sample, as well as awareness that multiple salivary gland pathologies can synchronously exist.

Indexed as

canalicular adenomahistopathologyoral and maxillofacial surgeryoral cavitypolymorphous adenocarcinomasalivary gland

Identifiers

PMID40755574
PMCPMC12316074

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.