ArticleOTA international : the open access journal of orthopaedic trauma2025
High mortality rates after distal femur fractures in patients with end-stage renal disease.
Article in OTA international : the open access journal of orthopaedic trauma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: Hip fractures in patients with end-stage renal disease (ESRD) are associated with high mortality rates. The effect of ESRD on mortality after operative treatment of distal femur fractures is not known. Our hypothesis was that distal femur fractures carry a similar mortality risk and complication rate compared with proximal femur fractures in patients with ESRD. Methods: Design: A retrospective database study using the United States Renal Data System registry. Setting: Not applicable. Patient Selection Criteria: Patients with ESRD who underwent operative fixation of proximal or distal femur fractures. Outcome Measures and Comparisons: All-cause mortality risk and survival rates were calculated using Kaplan-Meier analysis. The results were adjusted for potential confounding variables including age, body mass index, sex, comorbidities, and duration of dialysis. Complications were analyzed with the χ Results: In patients with ESRD who sustained a proximal (6118) or distal (430) femur fracture, the mortality rate was, respectively, 50.1% and 45.8% at 1 year ( Conclusions: In patients with ESRD, mortality rates after distal femur fractures were high and similar to mortality rates after hip fractures. Level of Evidence: Level III; retrospective cohort study.
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