Trial reportPhotodermatology, photoimmunology & photomedicine2025
Standardized In Vivo Method Using High-Resolution Diffuse Reflectance Spectroscopy for Evaluating Sunscreen Effectiveness Against Ultraviolet A and High-Energy Visible Light.
Trial report in Photodermatology, photoimmunology & photomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Standardized In Vivo Method Using High-Resolution Diffuse Reflectance Spectroscopy for Evaluating Sunscreen Effectiveness Against Ultraviolet A and High-Energy Visible Light.Photodermatology, photoimmunology & photomedicine · 2025Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundAccurate and reliable evaluation of sunscreen performance is necessary to ensure adequate balanced sun protection against ultraviolet light (UV) and high-energy visible light (HEV), depending on an individual's skin phototype and dermatoses. The objective of this study was to investigate the importance of methodological considerations for standardized evaluation of sunscreen performance to protect against UVA, especially long UVA1, and HEV.
methodsIn an open in vivo study, 6 commercial sunscreens were applied on the backs of subjects (n = 15) to evaluate the performance against UVA and HEV using a robust protocol of hybrid diffuse reflectance spectroscopy (HDRS), based on validated ISO methodology. High-resolution absorbance spectra were obtained between 310 and 450 nm using a 1 nm stepsize. The region 365-450 nm was compared with a method using linear interpolation from four discrete wavelengths (365, 405, 435 and 450 nm).
resultsThe sunscreen ranking observed using the in vivo high-resolution spectral representation (1 nm steps) method was not consistently reproduced by the method using four discrete wavelengths with linear interpolation. Differences between the two methods were observed in the range of 380-400 nm, leading to misclassification in the rank of protection depending on the methodology used.
conclusionsThe absorption profile in the UVA and HEV light ranges of each sunscreen was determined accurately and reliably by diffuse reflectance spectroscopy with measurements every nanometer. Sunscreen performance characterization will depend on the methodology, and applying linear interpolation from broader wavelength bands may give inaccurate results.
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