Evidence map›Paper›PMID 40755290›Full record

ArticleJournal of the American Chemical Society2025

Pushing Sensitivity and Specificity Limits in Native Structural Biology:

Kumar Tekwani Movellan, Daniel Banks, Christian Reiter, James G Kempf, Angela M Gronenborn, Tatyana Polenova

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Kumar Tekwani MovellanDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0002-8636-0087
Daniel BanksBruker Biospin Corporation, 15 Fortune Drive, Billerica, Massachusetts 01821, United States.ORCID 0000-0003-2352-7457
Christian ReiterBrukerBiospin GmbH & Co. KG, Rudolf-Plank-Str. 23, 76275 Ettlingen, Germany.
James G KempfBruker Biospin Corporation, 15 Fortune Drive, Billerica, Massachusetts 01821, United States.
Angela M GronenbornDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0001-9072-3525
Tatyana PolenovaDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0002-0346-1131

Funding

Project 3. IntegrationU54AI170791 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Peter Cherepanov · 2022 to 2026
$30.6M
NIAID NIH HHS U54 AI170791
6 · The paper itself

Abstract

Understanding protein structures and their interactions within natural cellular environments is essential for deciphering cellular processes and advancing therapeutic development. Obtaining atomic-level information about protein structural changes in cellular contexts poses a significant challenge. Here, we introduce a

Indexed as

Cyclophilin AFluorineNuclear Magnetic Resonance, BiomolecularCell Line, TumorHumansCyclophilin AFluorine

Identifiers

PMID40755290
PMCPMC12967303

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.