Evidence map›Paper›PMID 40755282›Full record

ArticleRenal failure2025

Incidence and risk factors for chronic kidney disease after hematopoietic stem cell transplantation.

Alina Tanase, Andreea Andronesi, Bogdan Sorohan, Andreea Vasile, Lavinia Lipan, Zsofia Varady, Laura Stefan, Oana Craciun, Adela Ranete, Bogdan Obrisca and 2 more

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alina TanaseBone Marrow Transplant Department, Fundeni Clinical Institute, Bucharest, Romania.ORCID 0000-0003-3075-499X
Andreea AndronesiNephrology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.ORCID 0000-0002-5590-7879
Bogdan SorohanNephrology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.ORCID 0000-0003-3574-4635
Andreea VasileNephrology Department, Fundeni Clinical Institute, Bucharest, Romania.
Lavinia LipanBone Marrow Transplant Department, Fundeni Clinical Institute, Bucharest, Romania.
Zsofia VaradyBone Marrow Transplant Department, Fundeni Clinical Institute, Bucharest, Romania.
Laura StefanBone Marrow Transplant Department, Fundeni Clinical Institute, Bucharest, Romania.
Oana CraciunBone Marrow Transplant Department, Fundeni Clinical Institute, Bucharest, Romania.
Adela RaneteBone Marrow Transplant Department, Fundeni Clinical Institute, Bucharest, Romania.
Bogdan ObriscaNephrology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.ORCID 0000-0003-4796-4950
Rebeca CioataIntensive Care Unit, Matei Bals National Institute of Infectious Diseases, Bucharest, Romania.
Gener IsmailNephrology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.ORCID 0000-0003-3306-189X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) in hematopoietic stem cell transplantation (HSCT) is becoming more common. Only few studies were published during the past 10 years. Identification of risk factors is of outmost importance.

objectivesWe assessed prospectively a cohort of 197 patients who underwent allogeneic HSCT, aiming to evaluate the incidence and risk factors associated with CKD. We registered the persistence of the low GFR. Cox proportional hazard analysis has been used to identify the risk factors. MAIN

resultsThe mean age was 38.7 years (52.8% female). Acute kidney injury was present in 80% patients within 3 months and CKD incidence was 11.7% with a median onset of 6 months. By univariate Cox regression analysis, age (per 1 year) was the only variable associated with CKD (HR= 1.06, 95%, CI= 1.02-1.10,

conclusionsAs the prognostic of hematopoietic stem cell transplantation survivors is improving, CKD emerges as an important comorbidity, with hematologic disease length and baseline eGFR being independent risk factors for renal dysfunction.

Indexed as

Acute Kidney InjuryHematopoietic Stem Cell TransplantationRenal Insufficiency, ChronicAdultAge FactorsCreatinineFemaleGlomerular Filtration RateHumansIncidenceMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk FactorsYoung AdultCreatinineChronic kidney diseasedialysisimmunosuppressionmarrow transplant

Identifiers

PMID40755282
PMCPMC12323005

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.