Evidence map›Paper›PMID 40755229›Full record

ArticleMovement disorders clinical practice2025

Split-Belt Treadmill for Falls, Gait Asymmetry, and Freezing in Parkinson's Disease.

Sanskriti Sasikumar, Gianluca Sorrento, Anthony E Lang, Antonio P Strafella, Alfonso Fasano

Abstract read
In one paragraph

Article in Movement disorders clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Sanskriti SasikumarDivision of Neurology, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-1538-1817
Gianluca SorrentoEdmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, UHN, Toronto, Ontario, Canada.
Anthony E LangDivision of Neurology, University of Toronto, Toronto, Ontario, Canada.
Antonio P StrafellaDivision of Neurology, University of Toronto, Toronto, Ontario, Canada.
Alfonso FasanoDivision of Neurology, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-5346-0180

Funding

CIHR 476290CIHR PJT- 173540
6 · The paper itself

Abstract

backgroundIndividuals with Parkinson's disease (PD) can adapt to new gait patterns on a split-belt treadmill (SBTM), a tool previously used to rehabilitate gait asymmetry because of stroke.

objectivesThe goal was to determine whether SBTM rehabilitation is superior to conventional "tied" treadmill (TM) in reducing falls, freezing of gait (FOG), and improving gait asymmetry.

methodsTwenty-eight participants with idiopathic PD and treatment-resistant FOG underwent 18 sessions of SBTM and TM training. Primary outcome was the incidence of falls 3 months after training, and secondary measures included spatiotemporal gait variables (treadmill and over-ground), motor scores, and performance on FOG and balance questionnaires.

resultsTreadmill training improved falls regardless of intervention (SBTM: P < 0.05; TM: P < 0.01), although benefits were not sustained at 3 months. SBTM did not meet the a priori 20% superiority threshold for falls prevention. Asymmetry index, temporal asymmetry, and stance time (P ≤ 0.01 in both groups) reduced after training. Swing time increased after training with both interventions (P ≤ 0.01). FOG and ABC scores also improved (P ≤ 0.01 in both groups), however, these improvements were not sustained at 3 months. Cadence and over-ground asymmetry index improved with both interventions (P ≤ 0.01), although only reduced cadence was sustained at 3 months (P = 0.05). Other over-ground parameters including gait velocity, stride length, double-support time improved with TM training only.

conclusionsSBTM was not superior to TM training in improving incidence of falls. Both interventions improved FOG and spatiotemporal gait parameters, although TM training translated better to over-ground walking.

Indexed as

Accidental FallsExercise TestExercise TherapyGait Disorders, NeurologicParkinson DiseaseAgedFemaleGaitHumansMaleMiddle AgedTreatment OutcomeexercisefreezinggaitParkinson's diseasesplit‐belt treadmill

Identifiers

PMID40755229
PMCPMC12625144

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.