Evidence map›Paper›PMID 40755225›Full record

ArticleGut microbes2025

Breastfeeding and the milk resistome shape the establishment and transmission of antibiotic resistance genes in the infant gut microbiome.

Zhe Pan, Calum J Walsh, Conor Feehily, Sai Ravi Chandra Nori, Fionnuala M McAuliffe, Paul D Cotter, John MacSharry, Douwe van Sinderen

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhe PanAPC Microbiome Ireland, University College Cork, Cork, Ireland.ORCID 0000-0003-3210-3023
Calum J WalshThe Centre for Pathogen Genomics, Department of Microbiology & Immunology, Peter Doherty Institute for Infection & Immunity, University of Melbourne, Melbourne, Australia.
Conor FeehilySchool of Infection and Immunity, University of Glasgow, Glasgow, UK.
Sai Ravi Chandra NoriAPC Microbiome Ireland, University College Cork, Cork, Ireland.ORCID 0000-0003-2553-3156
Fionnuala M McAuliffeUCD Perinatal Research Centre, School of Medicine, University College Dublin, National Maternity Hospital, Dublin, Ireland.ORCID 0000-0002-3477-6494
Paul D CotterAPC Microbiome Ireland, University College Cork, Cork, Ireland.ORCID 0000-0002-5465-9068
John MacSharryAPC Microbiome Ireland, University College Cork, Cork, Ireland.ORCID 0000-0002-9528-6261
Douwe van SinderenAPC Microbiome Ireland, University College Cork, Cork, Ireland.ORCID 0000-0003-1823-7957

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The infant resistome, the collection of antimicrobial resistance genes (ARGs) of newborns, is critical for gut microbiota establishment. Using metagenomic sequencing data, we analyzed various 1-week and 1-month postpartum samples to study infant resistome establishment, ARG transmission, and its impact on functional redundancy of the microbiota. A total of 431 samples were analyzed; infant stools (1-week,

Indexed as

BacteriaBreast FeedingDrug Resistance, BacterialGastrointestinal MicrobiomeMilk, HumanAnti-Bacterial AgentsFecesFemaleHumansInfantInfant, NewbornMetagenomicsAnti-Bacterial AgentsBifidobacteriumbreastfeedingdelivery modeearly resistomefunctional redundancyInfant resistomeresistome transmission

Identifiers

PMID40755225
PMCPMC12323436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.