Evidence map›Paper›PMID 40754982›Full record

ArticleHuman vaccines & immunotherapeutics2025

The influence of SARS-CoV-2 vaccination on in vitro fertilization outcomes.

Adi Anis Heusler, Amir Weintraub, Diana Stein, Yael Melamed-Yekel, Sarit Kalfon, Yael Pasternak, David Kulak

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adi Anis HeuslerThe Adelson School of Medicine, Ariel University, Ariel, Israel.
Amir WeintraubThe Adelson School of Medicine, Ariel University, Ariel, Israel.
Diana SteinIVF Unit, Department of OBGYN, Laniado Hospital, Netanya, Israel.
Yael Melamed-YekelThe Adelson School of Medicine, Ariel University, Ariel, Israel.
Sarit KalfonThe Adelson School of Medicine, Ariel University, Ariel, Israel.
Yael PasternakThe Adelson School of Medicine, Ariel University, Ariel, Israel.
David KulakThe Adelson School of Medicine, Ariel University, Ariel, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In December 2020, the FDA granted emergency use approval for 2 separate mRNA vaccines to combat the COVID-19 pandemic. While many questions as to the long-term safety of the vaccine were raised, this was particularly acute for those patients trying to conceive and among those utilizing assisted reproductive technologies. The study aimed to assess the effect of recent mRNA SARS-CoV-2 vaccination on IVF cycle outcomes. A retrospective case-control study, including all IVF patients under the age of 40 years in a hospital-based practice from January 1 to May 31, 2021. The study group included patients who received two doses of the Pfizer/BioNTech vaccine BNT162b2 SARS-COV-2 vaccine between 7 days to 6 months prior to starting IVF. The control group included unvaccinated patients from the same time period in the same year and in 3 previous years. IVF cycle results were compared between the groups. Three hundred and eighty-five women met the inclusion criteria; 349 in the control group and 36 in the vaccinated group. Demographic and clinical characteristics were comparable between the groups. The pregnancy rate was 33.3% (

Indexed as

BNT162 VaccineCOVID-19COVID-19 VaccinesFertilization in VitroVaccinationAdultCase-Control StudiesFemaleHumansPregnancyPregnancy RateRetrospective StudiesSARS-CoV-2BNT162 VaccineCOVID-19 VaccinesCOVID-19Covid vaccinefertilityIVFmRNA SARS-COV-2 vaccine

Identifiers

PMID40754982
PMCPMC12323424

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.